Ch 14 Lymphatic (Immune)
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Created by:
DrDavila Plus on June 20, 2012
Subjects:
BIO104: Human Anatomy & Physiology II
Description:
Dr Davila
Medical Careers Institute, ECPI University
Human Anatomy & Physiology II
BIO 104
Classes:
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41 terms
Terms | Definitions |
|---|---|
immune system function | 1. produce lymphocytes, which provide immunity;2. return lymph [interstitial fluid, or serum] and nutrients [eg, fat, electrolytes, etc.] to blood; 3. resist infection, or invasion of pathogens 4. remove and destroy cancerous cells and toxins |
pathogen | microscopic organsims that cause disease; eg, bacteria, viruses, fungi, parasites, |
immunity | ability to resist infection and disease |
lymph | watery fluid with leukocytes in lymphatic vessels;♪ serum-like fluid originally ejected from capillaries, bathed over cells as interstitial fluid, and seeped into lymphatics, becoming lymph. Same Fluid, 3 places♪ |
interstitial fluid | watery fluid between body cells; blood serum ejected from capillaries becomes interstitial fluid |
lymphatic vessels | vessels that carry lymph under low-pressure;similar to veins: thin wall, large lumen, valves; carry lymph from tissue to lymph nodes, then return to blood; aka lymphatics, |
right lymphatic duct | collects lymph from upper right quadrant of body; empties into right subclavian vein |
thoracic duct | collects lymph from remaining 3/4 of body: upper left quadrant and entire lower portion of body; empties into the left subclavian vein; aka left lymphatic duct, |
lymph node | encapsulated lymphatic organ located along lymph vessel;filter lymph for pathogens and cancer; lymphocytes may divide here [mitosis] causing swelling and firming; |
3 superficial lymph nodes | cervical, axillary, and inguinal lymph nodes;palpated to assist in diagnosis |
tonsils | 3 pairs of non-encapsulated lymphatic tissue found in oral cavity; palatine, adenoids, lingual; "front-line" protection against pathogens entering body; |
palatine tonsils | pair of non-encapsulated lymphatic tissue found on both lateral sides of soft palate [posterior roof of mouth] |
pharyngeal tonsils | pair of non-encapsulated lymphatic tissue in nasopharynx; aka adenoids |
lingual tonsils | pair of non-encapsulated lymphatic tissue found on posterior aspect of tongue; requires a tongue depressor to view clearly |
spleen | largest lymphatic organ found in LUQ of abdomen;filters old RBCs, and produces lymphocytes/monocytes: hence, it's pink; in fetus, also produces RBCs |
thymus | lymphatic organ superior to heart [looks like hat on heart]; T-lymphocytes mature here |
Peyer's patches | patches of lymphatic tissue in the ileum of small intestine; protect body from ingested pathogens |
natural immunity | immunity not specific to particular disease, will block or attack any pathogen; cannot distinguish one attack from another;eg, physical barriers (skin, mucus tears), fever, phagocytes, inflammation, aka innate immunity, |
acquired immunity | immunity to a disease that is not innate but has been acquired during life;formation of antibodies and lymphocytes after exposure to antigen; can be active or passive AND naturally-acquired or induced |
passive immunity | receiving antibodies made by another organism;eg, from mother or another animal for antivenom |
active immunity | organism actively makes its own antibodies;eg, after illness or vaccination |
naturally acquired active immunity | organism makes its own antibodies after naturally falling ill |
induced active immunity | organism makes its own antibodies after receiving a vaccination or inoculation |
naturally acquired passive immunity | organism receives antibodies made by its mother, either in the womb through placenta, or through mother's milk |
induced passive immunity | receiving antibodies made by another animal, as in antivenom;usually made in sheep, horse, or goat |
immunization | increasing resistance to infection by exposing body to inactivated pathogen and inducing active immunity |
autoimmune disorder | class of diseases in which the immune system targets normal body tissues and organs,eg Type 1 diabetes, multiple sclerosis, lupus |
allergy | exaggerated or inappropriate immune response to an allergen;aka hypersensitvity |
allergen | any antigen that may cause allergic response to occur; eg pollen, ant-bite venom |
anaphylaxis | life-threatening allergic reaction; symptoms include:1. bronchoconstriction [causes difficulty breathing], 2. vasodilation [causes hives, decreased blood pressure, generalized edema]; may lead to circulatory collapse [of blood vessels]; |
lymphocyte | 1 of 3 types of WBC (B-/T-/NK-lymphocyte)providing specific immunity (B & T) and some innate immunity (NK);smallest WBCs; 25% of total WBC population |
B lymphocyte | differentiates in bone; makes antibodies performing antibody-mediated immunity; aka plasma cell |
T lymphocyte | differentiates in thymus;performs cell-mediated immunity |
NK cell | type of lymphocyte performing a nonsppecific immunity called immunological surveillance;kills viuses, other pathogens, and canerous cells |
antigen | any substance (toxin, cell-surface protein) that stimulates production of antibodies; "anything body may see as foreign" |
antibody | immunoglobulin protein released by B-lymphocytes in response to antigen; antibody sticks to antigen; antibody signals phagocytic eosinophils |
immunoglobulin | class of proteins produced by B-lymphocytes, which function as antibodies; 5 types: IgG most common IgM "prototype" antibody |
nonspecific defense | block or attack any potential pathogen; cannot distinguish one attack from another, so acts characteristically regardless |
7 nonspecific defenses | Physical barriersInflammation Fever Phagocytes Immunological surveillance Complement Interferons |
inflammation | body tissue response to injury or irritation; 4 signs: *swelling pain redness heat* |
blood borne infections | blood-borne infections (ie HIV and Hepatitis C) require intimate contact with blood or other body fluids; casual contact with hands, food, or sneezes cannot transmit these diseases |
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