Diseases of Immunity
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Created by:
luvsmusic56 on June 28, 2012
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21 terms
Terms | Definitions |
|---|---|
 ANY ROUND CELL WITH RATHER DENSE STAINING CYTOPLASM AND MINIMAL CYTOPLASM IN CONNECTIVE TISSUE, A BIT BIGGER THAN AN RBC, | LYMPHOCYTE |
| Antibody secretion | Plasma Cell |
| Killing infected cell | CD 8 |
| Stimulate B lymphocyte, inflammation, activation of macrophages | CD4 |
| FLT-3 ligand TNF-a TGFβ | Common lymphoid progenitor to small lymphocyte (which can turn into B lymphoctyte...need IL 1,2,4,6,7 to become a T lymphocyte). |
| Tpo= Thrombopoietin | Megakaryocyte to thrombocytes |
| Epo= erythropoietin | Erythrocyte |
| Granulocyte-macrophage colony-stimulating factor (GM-CSF) | Common myeloid progenitor to myeloblast to basophil, neutrophil, esoinophil, monocyte |
| IL 15 | Natural Kill cell made in Bone Marrow |
| Flt 3L | Plasma Cell production in the bone marrow |
| IL 7 | T cells made |
| Structure of T Cell Receptor | disulfide-linked heterodimer made up of an α and a β polypeptide chain, CD3 complex, zeta chain dimer |
| MHC Restriction | specificity of T cells for peptides displayed by the cell surgace MHC molecules |
| Aids T cell ratio | CD4 : CD8 is .5:1 instead of 2:1 ratio. |
| Signals needed for T Cell Activation | 1. TCR + MHC & CD4/8 + MHC 2. CD 28 on T Cell + B7-1 (CD80)/ B7-2 (CD 86) |
| IL 2 | T cells proliferate |
| What does CD 4 TH1 cell secrete? | IL 2 and IFN gamma. Activate macrophages and type IV hypersensitivity. |
| CD4 TH 2 cell secretion | IL 4, IL 5, IL 13. Type I hypersensitivy & Eosinophils |
| Ig alpha, Ig beta, IgM, IgD, CD 28 | B cell receptor |
| CR2, CD 21 | Type 2 complement receptor B lymphocyte, receptor for the Epstein- Barr Virus (Ebv readily infects B cells) |
| ANY CELL MIXED IN WITH LYMPHOCYTES BUT HAS A LARGER MORE "OPEN", LESS DENSE, LESS CIRCULAR NUCLEUS WITH MORE CYTOPLASM IS A | Macrophage |
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