DOCs/first line

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Created by:

kasegars Plus on July 13, 2012

Subjects:

pharm

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DOCs/first line

Penicillin G (Pfizerpen) DOC
syphillis - treponema pallidum (gm - spiro)

gas gangrene - clostridium perfringens (gm +rod)
1/31
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Penicillin G (Pfizerpen) DOC syphillis - treponema pallidum (gm - spiro)

gas gangrene - clostridium perfringens (gm +rod)
Ampicillin DOC listeria monocytogentes (gm+rod)
Ticarcillin (Timentin) FLA pseudomonas aeruginosa gm - rod
Piperacillin/ taxobactam sodium (zosyn) FLA pseudomonas aeruginosa gm - rod (more potent than ticarcillin)
Cefazolin DOC surgical prophylaxis for ortho surgery
Cefoxitin FLA bacteroides (gm-rod)
mixed anaerobic infections - peritonitis and diverticulitis
Ceftriaxone (Rocephin) FLA (4) neisseria gonorrhea gm-cocci
haemophilus influenza gram - rod (meningitis)
PCN-resistant strep pneumo gm +cocci
typhoid fever salmonella typhi gm - rod
Cefotaxime FLA HiB gm -rod (meningitis)
PCN-resistant strp pneumo
Cephalosporins in general are the DOC for UTIs and pneumonia caused by ________________________ klebsiella pneumonia
Cefotetan bad complication bleedin in the teeths - hypothrombinemia and bleeding disorders.
ceftazidime FLA pseudomonas aeruginosa gm - rod
cefixime FLA neisseria gonorrhea gm - cocci
Cefepime FLA psuedomonas aeruginosa
DOC (2) for neonatal and childhood meningitis caused by Hib ceftriaxone, cefotaxime
Doxycycline DOC (7) Rickettsia (Rocky mountain and typhus) gm -
chlamydia pistachio
chlamydia trachnomatic LGV gm -
ureaplasma urealyticum
mycoplasma pneumonia
borrelia burgdorferi
calymmatobacterium granuloma

doxy the rickety clam eats pistachios and urinates in lyme, CT and calyfornia
Doxycycline FLA (3) cholera
brucellosis
chlamydia pneumonia
Doxycycline back up agent (4) legionella
chanchroid haemophilus ducreyi
tetanus
gas gangrene
Tetracycline of choice in patients with renal failure doxycycline
FLA tetracycline in patients with reduced renal function tigecycline
what two gram + cocci should you NOT use with an aminoglycoside? strep pyogenes, strp pneumo
Streptomycin DOC (2) yersinia pestis (with tetracycline) gm - rod
francisella tularensis gm - rod
Gentamicin DOC (combo) endocarditis and bacteremia due to enterococcus

with PCNG, amp or vanc
Gentamicin FLA (2 dz and 4 agents) endocarditis and bacteremia due to:

viridans strep
listeria mono
campylobacter fetus
brucellosis (with doxy!)
Tobramycin FLA (3 dz and 1 agent - combo) bacteremia, pneumonia, UTI due to

pseudomonas aeruginosa (with PCN, ceftazidime or cefepime)
Ceftaroline (teflaro) 4 things it can treat that not many others can MRSA
VISA
VRSA
enterococcus faecalis

community acquired pneu
what is most widely Rx 3rd gen ceph? cefdinir - kids love to eat dinir!

pediatric patients for skin and soft tissue and otitis media
Cefepime FLA pseudomonas aeruginosa (UTI, pneumonia, bacteremia, meningitis)


can also use for intraabdominal infections
DOC for neonatal or childhood meningitis due to haemophilus influenza ceftriaxone, ceftaxime
what cephalosporin can you use for patients with decreased renal function? ceftriaxone
what can you treat with aztreonam ? ANY AEROBIC gram - bacilli - particularly pseudomonas for CF patients (inhale - cayston)

UTI and RTI
all cephalosporins are active against what 3 organisms? proteus, ecoli, klebsiella

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