Dr. B Chp. 22 Pharm Anticonvulsants
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13 terms
Terms | Definitions |
|---|---|
 anticonvulsants drugs | Neurotin,Tagretol,Lamictal |
| Purpose for anticonvulsants | commonly used for the management of nerve pain associated with neuralaia, Herpes Zoster(shinges), and cancer, pain is sharp, shooting, shock-like or lightning-like |
| side effects of anticonvlsants | sedation, dizziness and confusion, nausa, vomiting, constipation, anorexia, ataxia and unsteadiness, Hepatitis(not Lyrica), rash, stevens-johnson syndrome(Lamictal- start slow, slow titration upward), bone marrow suppression, nystagmus, diplopia(double vision) and blurred vision, gingvitis(gabapentin), weight gain and peripherial edem(pregablin |
| gabapentin | Neurotin |
| carbamazepine | Tegretol |
| lamotrigine | Lamictal |
| Caution with anticonvulsants | if used with allergies, hepatitis, cardiac and renal disease, Do Not confuse Lamictal with Lamisil |
| Contraindications for anticonvulsants | hypersensitivity, psychiatric conditions(increased risk od suicidal thoughts), pregnancy, SA(sinostrial) and AV(atrioventricular) block Tegretol, hemolytic disorders, abrupt discontiuation |
| Interactons with anticonvulsants | alcohol decreases effects, antacids decrease effects with Neurotin, antineoplastics decreased effects with Tegretol, CNS depressants decreased effects with Tegretol, folic acid decreased effects with Lamictal, ACE inhibitors and Lyrica nreased risk of angioedema, antiretrovirals increased or decreased effects with Lamictal and Tegretol |
| Depakot (valproic acid) | broad-spectrum anticonvulsant |
| Purpse of Depakot | management of any seizure types including generalized tonic-clonic, absence and myoclonic seizures |
| side effects of Depakote | weight gain, dyspepsia, alopecia, rash, tremor, hepatotoxicity, pancreatitis, blood dyscrasias |
| interactions with Depakote | grbamazepine, phenytoin, phenobarital and topiramte which decreases valproic acid levels, amitriptylineand nortriptyline which increases valproic acid levels |
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