| Term | Definition |
| apo/b100 | better predictor of cad in women |
| apo | vehicles for cholesterol |
| apo A1 | good cholesterol |
| vldl | raise the risk of heart attack and angina |
| ldl | contain more fat and less protein, unstable, fall apart |
| hdl | carry cholesterol away from the arteries and back to liver |
| optimum cholesterol ratio | 3.5:1 |
| #1 killer in women | heart disease |
| statins | first line of defense for post-menopausal with cad |
| 1drug categories for hyperlipidemia | 1bile acid derivatives-resins |
| 2drug categories for hyperlipidemia | 2 niacin |
| 3drug categories for hyperlipidemia | 3 fribric acid derivatives |
| 4drug categories for hyperlipidemia | 4HMG CoA Reductase Inhibitors-statin |
| 5drug categories for hyperlipidemia | 5 cholesterol absorption inhibitors |
| questran | bile acid derivative |
| nicotinic acid | inhibits synthesis and secretion of vldl and ldl |
| increases hdl | nicotinic acid, fibric acid |
| fibric acid derivatives | lopid |
| fibric acid | decreases synthesis and secretions of vldl and triglycerides |
| lopid | increases effects of anticoagulants and hypoglycemics |
| implications for lopid | watch blood sugars, watch for bleeding, check alt test |
| questran interferes with absorption of | digoxin, beta blocker, vanco, vitamins |
| HMG CoA reductase inhibitors | blocks synthesis of cholesterol, decreases inflammation |
| Implications for HMG CoA reductase inhibitors | monitor liver enzymes, monitor eye exams |
| HMG CoA reductase inhibitors most effective | zocor and lipitor |
| action of cholesterol absorption inhibitors | inhibits absorption of dietary and biliary cholesterol across intestinal wall |
| action of cholesterol absorption inhibitors | zetia |
| contraindications for cholesterol absorption inhibitors | those with liver disease taking statins |
| Complimentary/alteranative therapy | garlic, omega-3 fatty acids, fiber, 30 min exercise |
| hypertensive | 140 systolic 80 diastolic |
| prehypertensive | 130-139 systolic and 80-89 diastolic |
| risk for cad begins at | 115/75 |
| risks of sleep apnea | cad, stroke and heart failure |
| target organs of prolonged htn | heart, brain, peripheral vasculature, kidneys, eyes |
| first line drugs of htn | diuretics, beta-blockers, angiotensin inhibitors, andrenergic receptor blockers, calcium channel blockers |
| apolipoproteins transport | tryglycerides and cholersterol through the blood stream |
| first line for post menopausal women | statins |
| zetia is contraindicated for | active liver disease and those taking statins |
| 130/80 with kidney disease or diabetes | will be treated for hypertension |
| questrian | binds with acids in intestine that will be excreted in feces |
| QUESTRIANS | remove ldl |
| diurinal variable | highest in am, decreases, lowest at night |
| early manifestations of htn | nocturia |
| htn drugs | diuretics, beta blockers, adrenergic receptor blockers, ca channel blockers |
| nursing implications for beta blockers | check pulse before giving |