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5 Written Questions

5 Matching Questions

  1. aMSH present
  2. Leptin (greek for thin)
  3. Polydipsia
  4. Effects of insulin on adipose cells
  5. Large fat cells
  1. a produce more leptin to eat less
  2. b Inc thirst due to dehydration
  3. c inc glucose uptake and use, glycerol synthesis, FFA uptake (via stimulating lipoprotein lipase in endothelial cells); dec lipolysis in fat cells via inhibiting lipases
  4. d released from adipose cells; gene termed -ob for obese
  5. e MSH binds to melanocortin1 receptor; inc in cAMP dec "free" Ca2+ causing relaxation of melanofilaments which allow melanosomes to spread, causing skin to darken

5 Multiple Choice Questions

  1. enzye, acid/base secretion; smooth muscle contraction; horm release from pancreatic islets; growth promoting actions
  2. dec blood Ca by acting on bone to inhibit osteoclast activity; produced by C cells (parafollicular cells that arise from ultimobranchial glands in mammals, migrate to thyroid gland) located in thyroid gland
  3. Sulfonylureas (ex: carbutamide, tolbutamid) close K+ ATP channels whic open Ca2+ channels; free Ca 2+ stimulates insulin release form B cells
  4. via larger proteins called neurophysins: Vasopressin neurophysin = pressophysin, oxytocin NP = oxyphysin, cleaved off during axonal transport, secreted with neurohormones
  5. rickets (failure in kids) osteomalacia (in adults) Paget's dz ( weak bones due to excessive osteoclasts)

5 True/False Questions

  1. Hormone synthesizing cellsosteoblasts (new bone formation); osteoclasts (bone breakdown, 18% Ca in bone now replaced in one year)

          

  2. ACTH fxnstimulates glucocorticoid synthesis in adrenal cortex

          

  3. PTH - parathyroid hormpolypeptide essential for life; fxns to inc blood CA levels, produced by chief cells of parathyroid gland;

          

  4. Effects of PRL on reproductioninc glucose uptake via GLUT-4, glucose storage in glycogen, AA uptake and protein sythesis

          

  5. Metabolic sydrome, associated with DM2High fasting BSG; High triglyceride levels; low blood high density lipoprotein (HDL); HTN

          

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