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5 Written questions

5 Matching questions

  1. Calcitonin (CT)
  2. Transport of neurohypophysial horms
  3. Factors stimulating glucagon release
  4. Food intake and MSH
  5. Prolonged hypoglycemia damage
  1. a dec blood Ca by acting on bone to inhibit osteoclast activity; produced by C cells (parafollicular cells that arise from ultimobranchial glands in mammals, migrate to thyroid gland) located in thyroid gland
  2. b glycosylation of proteins, formation of sorbitol from glucose
  3. c aMSH binding to melanocortin4 reduces food intake (inc leptin, inc MSH); inhibition of Mc4r causes overeating and obesity (Agouti protein inhibits Mc4r)
  4. d via larger proteins called neurophysins: Vasopressin neurophysin = pressophysin, oxytocin NP = oxyphysin, cleaved off during axonal transport, secreted with neurohormones
  5. e hypoglycemia; AA (arginine and alanine blocked by glucose); Epi, norepi

5 Multiple choice questions

  1. stimulate release of TSH in homeotherms (mammals/birds); useful to test ability of pituitary to produce TSH
  2. increase Ca mobilization from bone; stimulate osteoblasts to release osteoclast diff inducing factore (IL-6) that cause osteoclasts to release acid proteases whichd digest bone matrix; stimulates differentiation of precursor cells to osteoclasts
  3. uremia, renal failure, MI, CVA, blindness, gangrene, PVD, impotence (loss of small vessel/nerves), failure of wounds to heal, tissue damage from hyperglycemia
  4. glucose exceeds tubular max, excess remain in urine
  5. hypercalcemic agent produced by tumors, nl physio fxns in growth and development (inc fetal serum Ca, tooth eruption, mammary gland development)

5 True/False questions

  1. NucleusF (stimulate development of ovarian follicles) M (stimulate synthesis of androgen binding protein in sertolli cells, formation of LH receptors in Leydig cells)


  2. HyposecretionNeoplastic tumor of hormone producing cells, most common in microadenonas


  3. PTH - parathyroid hormpolypeptide essential for life; fxns to inc blood CA levels, produced by chief cells of parathyroid gland;


  4. Xanthophoresstain with basic dyes (TSH, FSH, LH, ACTH)


  5. CCK fxnsgallbladder contractions, relaxation of sphincter of oddi, inhibition of gastric emptying, inc pancreatic enzyme secretion and bicarb secretion, stimulates growth exocrine pancreas


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