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5 Written questions

5 Matching questions

  1. PTH action on intestine
  2. Clinical importance GnRH
  3. Category 3 horm's (ACTH, aMSH, BLPH)
  4. Category 1 hormones (GH, PRL)
  5. Hypersecretion
  1. a derived from pro-opiomelanocortin (POMC)
  2. b similar size (191/199); common AA
  3. c induce ovulation; treat oligospermia, constant exposure causes gonadotrope desensitization; GnRH longacting analogs = antifertility agent
  4. d acts indirectly to inc CA2+ and PO4 uptake by activating 1a-hydroxylate enzyme required to form 1a,25(OH)2D3
  5. e Neoplastic tumor of hormone producing cells, most common in microadenonas

5 Multiple choice questions

  1. F (stimulates ovulation, corpus luteum formation, estrogen synthesis) M (stimulates T synthesis by Leydig cells)
  2. rickets (failure in kids) osteomalacia (in adults) Paget's dz ( weak bones due to excessive osteoclasts)
  3. excess glucose in blood binds to proteins, glycosylated proteins accumulate in eye membranes, kidneys, nerves, vascular system and other organs, inhibi nl fxn
  4. Haptic blutathione insulin dehydrogenase (liver) separates A and B chains; half life is about 5 min
  5. stimulates glucocorticoid synthesis in adrenal cortex

5 True/False questions

  1. Vitamin D3/D2Prehormones for 1,25(OH)2D3; Vit D3 (cholecalciferol) synthesized in skin from 7-dehydrocholesterol upon exposure to UVB, also in animal tissue; Ergocalciferol (D2) from plants can be used to form 1,25(OH)2D3


  2. TriglyceridesBroken down by lipases to glycerol and FFA; Glycerol converted to glucose by gluconeogenesis, FFA converted to acetyl CoA by glucose sparing


  3. FSH fxnsstimulates thyroid gland


  4. GH related dzDwarfism (underproduction); Gigantism (excess GH, linear bone growth); Acromegaly (excess GH in adults)


  5. aMSH fxnaffects pigmentation via cation of malanophores


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