Cells and Structures: the Anatomy of the Nervous System
What do "Golgi Stains" help visualize?
What do "Nissl stains" help visualize?
What does "Immunocytochemistry/ immunofluorescence" help detect?
And how does it work?
What is "Autoradiography"?
What is "Situ Hybridization"?
|What are "Immediate early genes (IEG)s?|| genes that are expressed when cells first become active|
c-fos is the most widely used of IEGs
By using immunocytochemistry (ICC) to label the IEG product, researches can identify brain regions that were active
|What is "Anterograde Labeling"?||Anterograde labelinig uses radioactive molecules which are taken up by the cell and then transported to the axon tips|
What is "Retrograde Labeling?
|Retrograde labeling uses horseradish peroxidase (HRP) which is taken up in the axon terminals and transported to the cell bodies, then visualized through chemical reactions|
What are the four mane zones of a neuron?
What are the three general shapes or neurons?
| Multipolar - one axon, many dendrites; most common type|
Bipolar neurons - one axon, one dendrite
Unipolar neurons - a single extension branches in two directions, forming an input zone and an output zone
What is "Axonal transport"?
|The bidriectionial movement of materials within an axon|
|What is the name of the disease which consists of a demyelination of neurons?||Multiple Sclerosis|
|Name the four most common Glial cells|| Oligodendrocytes - mylein sheat of CNS|
Schwann Cells - myelin sheath of PNS
Astrocytes - contribute to Blood brain barrier
Microglial cells - clean debris
What are 6 functions of an Astrocyte?
|How much of our total oxygen is consumed by the brain?||20%|
What is Korsakoff's syndrome?