| Term | Definition |
|---|
| >15mm | positive in those with no risk for TB |
| >10mm | positive in recent immigrants, IV drug users, health care employees, chronic dz, |
| >5mm | HIV positive people, fibrosis on CXR, recent contact with active TB, organ xplant, prednisone >1mth |
| booster phenomenon | latent TB pt with negative PPD test d/t short incubation period |
| false positive | BCG vaccine, other myco |
| false negative | HIV infxn, corticosteroids, malnutrition |
| quanteferon gold | IFN-y; less reactive with BCG and other myco |
| quanteferon gold | not for use in pregnant women or kids |
| INH | can cause peripheral neuropathy, hepatitis |
| rifampin, rifapentine | can cause GI upset, hepatitis; colors urine |
| ethambutol | can cause optic neuritis; red/green color blindness |
| pyrazinamide | can cause hepatitis, hyperuricemia |
| latent TB | 9 months INH, 4 months rifampin |
| new PPD+ test, contact with active TB, PPD+ of unknown duration (<35yo), PPD+ and HIV | INH or INH/RIF or INH/PZA |
| active TB | [INH + rifampin + ethambutol + pyrazinamide] 2 months + [INH + rifampin] 4-6 more months |
| multi-drug resistant TB | INH + rifampin resistance |
| extensively drug resistant TB | INH + RIH + 3 second line drugs |
| pediatrics | INH + RIH + PZA |
| pregnancy | INH + RIH + ethambutol + pyroxidine |
Combine with other sets
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