| Term | Definition |
| Pure Substance | When all particles are alike in a substance. |
| Elements | Simplest pure substance. |
| Atom | Smallest particle of a substance with all of its properties. |
| Chemical Symbols | Shorthand names for elements. |
| Compound | Two or more different atoms chemically bonded. |
| Molecule | Two or more atoms chemically bonded. |
| Chemical Equation | A way to show a chemical reaction. |
| Subatomic Particles | Particles smaller than an atom. |
| Protons | Positively charged particles. |
| Neutron | A subatomic particle with no charge. |
| Electron | Negatively charged particle |
| Atomic Mass Unit | The unit of measuring for atoms. |
| Nucleus | Accounts for most of the mass of an atom. Made of Protons and Neutrons. |
| Atomic Number | The number of protons in the nucleus of an atom. |
| Isotope | An atom with the same atomic number, but different number of neutrons. |
| Mass Number | The sum of neutrons and protons in one nucleus. |
| Atomic Mass | Average mass of isotopes as they are found in nature. |
| Ion | An atom that is positively or negatively charged. |
| Electron Cloud | Where the electrons can be found in an atom. |
| Quark | The subatomic particle that makes up neutrons and protons. |