5 Written Questions

1. Increases uric acid secretion - used in gout
2. Inhibits uric acid synthesis - used in gout
3. Blocks tyrosine hydroxylase (which converts L-tyrosine to DOPA
4. MAO-B Inhibitor
5. Prevents production of folate in bacteria for nucleic acid synthesis - widely used for UTIs

5 Matching Questions

1. Prednisolone
2. Carbachol
3. Metronidazole/Tinidazole
4. Nefadazone
5. Cushings syndrome

1. a State of excess glucocorticoids
2. b 5-Nitroimidazoles - Produce chemically reactive intermediates, which damage/impair synthesis of prokaryotis DNA - used for anaerobic bacteria and some protozoa
3. c M4/M5 Agonist
4. d Synthetic steroids
5. e 5HT2A blocker/5HT uptake inhibitor - used in depression

5 Multiple Choice Questions

1. M3 Agonist
   1. Lidocaine/Lignocaine
   2. Carbachol
   3. Pilocarpine/Bethanechol
   4. Tolcapone/Entacapone
2. Cephalosporins - all are quite similar, used as broad spectrum antibacterials
   1. Metronidazole/Tinidazole
   2. Flucloxacillin/Methicillin
   3. Cefadroxil/Cefuroxime/Ceftazidime/Ceftriaone
   4. Tolcapone/Entacapone
3. Vasoconstrictor accompanying local anaesthetic - ensures effects remain local
   1. Pilocarpine/Bethanechol
   2. Adrenaline/Felypressin
   3. Donepezil
   4. Lidocaine/Lignocaine
4. NMJ Nicotinic Agonist
   1. Ondansetron
   2. Trimethoprim
   3. Suxamethonium
   4. Amethocaine
5. Phase of metabolism that involves oxidation (Less commonly reduction/hydrolysis)
   1. Phase I Metabolism
   2. Trimethoprim
   3. Phase II Metabolism
   4. Suxamethonium

5 True/False Questions

1. Ketamine/PCP → NMDA (Glutaminergic receptor) blockers

   True        False

2. Phenoxymethylpenicillin → Inhibits cell wall production of bacteria - Used as narrow spectrum for Gram +ve bacteria, esp. streptococcal, pneumococcal, meningococcal, leptospiral infections

   True        False

3. Co-Amoxiclav → Ester local anaesthetic

   True        False

4. Cortisone/Hydrocortisone → Natural glucocorticoids

   True        False

5. Chloramphenicol → Inhibits peptidyl transferase - broad spectrum

   True        False