| Term | Definition |
| Adad | god of weather: rain, storm, flood |
| Annunaki | gods of the underworld; gods who judge the dead |
| Anu (An) | father of gods; god of the firmament; got earth stolen by Enlil; faded into background; has temple in Uruk |
| Dumuzi | god of fertility, vegetation; associated with shepherds |
| Ea (Enki) | god of all gods; god of sweet waters, wisdom; patron of arts; one of the creators of mankind; son of Anu; liked to help humans |
| Enlil | god of earth, wind, water, universal air; took over after Anu |
| Ennugi | god of irrigation; inspects canals (so crop will be good) |
| Ereshkigal | queen of the underworld; formerly a sky-goddess; counterpart of Persephone; part of Annunaki |
| Ishtar (Inanna) | goddess of war, love, fertility; queen of heaven; associated closely with Uruk |
| Lugalbanda | Gilgamesh's father (protector); shepherd; king of Uruk after flood; in Sumerian poems |
| Namtar | demon of underworld; bringer of disease and pestilence |
| Nergal | god of underworld, plagues, fire; husband of Ereshkigal; similar to Namtar |
| Ningirsu | god of fertility, irrigation, fields; child of a she-goat |
| Ninlil | goddess of heaven, earth, air; mother of moon; female counterpart of Enlil |
| Ninsun | Gilgamesh's mother; had wisdom; creator of myth |
| Ninurta | god of wells, irrigation, winds, war; messenger; connected to man controlling waters; warrior |
| Ninhursag | mother goddess; goddess of mountains, birth, vegetation; created Earth; one of the four main gods |
| Shamash | sun god of justice; "lawyer"; son of Sin |
| Sin | god of moon; controls lunar cycle (the months) |