Set: Chapter 40: Cell Signals

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All 37 terms

TermDefinition
transcription factorswhen a hormone binds to a receptor and causes a conformational change
hormone receptor independentlow mw allows it to pass through the membrane and acts on it directly
examples of secondary messengersCa2+, cAMP, cGMP
first messengershormones that don't act on the target cell
second messengershormones that act on the target cell
NO activatesguanalate cylase to produce cGMP
g-protein interacts withc-terminal
Gs on beta receptoractivates GRK
GRKacts on the third loop and causes termination of the signal
active state of g-proteinsGTP attached to the alpha subunit
inactive state of g-proteinsGDP attached to the alpha subunit
receptor kinase outside binds withinsulin
receptor kinase inside binds withtyr kinase
Guanylate cyclasemakes cGMP
Gi comprises ofGi, Go, Gz
Whopping cough inactivatesGi which leaves Gs stimulated causing coughing
Gq comprises ofGq, G11, G14, G15, G16
G12 comprises ofG12, Goff, G13
Gs Comprises ofGs, Gt, Ggust
Gt is locatedretina
Ggust locatedtaste buds
Cholera toxin effectsGs which activates cAMP which draws fluid from the body in the GI tract
epinephrine at beta receptorstimulates Gs making cAMP
epinephrine at alpha receptoractivates Gi lowering cAMP
theopthyline and caffine inhibitcAMP to 5'AMP
Calmodulin co-factorCa2+
MLCK co-factorCa2+ and calmodulin
Classical PKCrequires Ca2+ and DAG for activation
Novel PKCrequires DAG for activation
Atypical PKCdoes not require DAG or Ca2+ for activation
PLA2 on phoshatidylcholineproduces lysophoshatidyl choline and fatty acids
PLC on phoshatidylcholineproduces DAG and choline-PO4
PLD on phoshatidylcholineproduces phsphatidic acid and choline
Eicosanoids areautocrines
eicosanoids consist ofprostaglandins, prostacyclin, thromboxane, and leukotrienes
phosphatidyl choline ----> arachidonic acidPLA2
arachidonic acid -----> leukotrieneslipoxygenase

Set Information

Terms 37
Creator atlevine
Created November 5, 2009
Group UH BSPS 2011
Subject biochemistry
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LKLeng : hey, just fyi, I think NO activates guanalate cylase to produce cGMP.
Last Message: 15 days ago

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Most Missed Words

  1. PLA2 on phoshatidylcholine produces lysophoshatidyl choline and fatty acids - 2 misses
  2. examples of secondary messengers Ca2+, cAMP, cGMP - 2 misses
  3. Eicosanoids are autocrines - 2 misses
  4. Gq comprises of Gq, G11, G14, G15, G16 - 2 misses
  5. Cholera toxin effects Gs which activates cAMP which draws fluid from the body in the GI tract - 2 misses
  6. PLC on phoshatidylcholine produces DAG and choline-PO4 - 2 misses
  7. epinephrine at alpha receptor activates Gi lowering cAMP - 2 misses