Anatomy & Function

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Created by:

dogdig  on September 29, 2012

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Anatomy and Function

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The study of the Human body

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Anatomy & Function

Ascites
Fluid Accumulation in the Peritoneal Cavity. People with liver disease produce reduced levels of albumin resulting in water leaking out of blood vessels into the abdominal cavity.
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Ascites Fluid Accumulation in the Peritoneal Cavity. People with liver disease produce reduced levels of albumin resulting in water leaking out of blood vessels into the abdominal cavity.
Negative Feedback Maintains Homeostasis - Good =D
Keeps body conditions within normal range
positive feedback Drastic Changes - Bad D=
Increases change
Often fatal as in the case of Cardiogenic Shock
Sometimes useful, as in the case of Labor or Birth
Cells ATP- Energy source for all cell reactions
Proteins
DNA
ATP Energy source for all cell reactions
Energy in ATP comes from the 3 Phosphate bounds - ATP, ADP, AMP
Cells can store energy by adding Phosphates to AMP and ADP to make ATP.
protiens Proteins are produced by cells and differ in their function according to their shape wide variety of protein functions: Signaling Proteins, Structural Proteins, Proteins with immune system functions... Etc.
Denatural proteins are proteins whose shape has been destroyed and no longer functional.
DNA The molecule that contains all of our genetic information.
Cell Membrane Consists of a Phospholipical bilayer that is selectively permeable
controls what goes in & out of cell
Diffusion The movement of molecules from a high concentration to a lower concentration
Osmosis Diffusion of just water
Dialysis Diffusion of just solids (Proteins... Etc.)
Hypotonic Solution has a higher concentration of water than the cell
hypertonic solution has a lower concentration of water than the cell
Isotonic Solution Has the same water concentration as the cell
Ex. IV fluids need to be isotonic
Superior Towards head
Pleural Cavity Lungs
Inferior Towards feet
Medial Median or Center
Lateral Towards sides
Proximal Feet > Hands > Head
Arms & Legs
Distal Head > Hands > Feet
Arms & Legs
Superficial Shallow Cut
Deep Cut Cut through the muscle
Levels of Structure Molecules > Cells > Tissues > Organs > Organ System > Whole body
Transverse of Cross Section Horizontal Cut
Frontal Back & Front
Mid -Sagital Down the spine
Left & Right
Para - Sagital 3 Unequal Sections
Cranial Cavity Brain
Vertical or Spinal Cavity Spinal Cord
Abdominal Cavity All organs below the lungs
Pericardial Cavity Heart
Serous Membranes Prevents friction and allows organs to move easily within their cavities.
Visceral Serosa Lines the organs surface
Thoracic Cavity Diaphragm
Parietal Serosa Lines the Cavities surface
Visceral Membrane touching the Organ
Parietal Membrane touching the cavity
Visceral Pleura & Parietal Pleura Membranes around the Lungs
Visceral Pericardium & Parietal Pericardium Membranes around the Heart
Visceral Peritonieum & Parietal Peritonieum Membranes around the Abdomen
Pericarditis Inflammation from trauma or infection
Inflates the Pericardial cavity with excess fluid
heart is squeezed and cannot refill
Circulation stops
Death occurs unless a needle is used to remove the excess fluid from the pericardial cavity
peritonitis Results from infection - Ruptured Appendix. Pelvic Inflammatory disease Etc.
Causes abdominal organs to become adhesive which makes them stick together
Causes septic shock
Nucleaus Cells nucleus contains DNA
Mitosis Cell division without genetic recombination
The process of mitosis creates a new cells needed for growth and replaces older cells that are no longer functional
Takes about 7 hours
in healthy cells, it only occurs when needed
Interphase Majority of Cells life is spent here
Prophase Cell begins the process of division
1. Chromosomes condenses & become visible
2. Nuclear envelope disappears, Nuclear envelope is the membrane around nucleus
3. The mitotic spindles begin to form. These are the rope like structures which will pull the chromosomes apart
Metaphase Second Stage of Mitosis
a short resting period where the chromosomes are lined up along the mid-line of the cell, with chromosomes at opposite ends of the mitotic spindle is fully formed
Anaphase 3rd Stage
the sister chromatids of each chromosome divide
the mitotic spindle fibers contract and the chromosomes are pulled
Telephase 4th Stage
Entire cell divides
chromosomes are at the poles of the spindle
spindle disintegrates
nuclear envelope reforms around the 2 sets of chromosomes
cytoplasm is divided into 2 separate cells through the process of cytokinesis.
Cancer a form of uncontrolled mitosis
P53 intact and sends signal but the other gene doesn't respond or it loses P53.
Cancer Treatment Cut it out or radiation or chemicals to kill actively dividing cells.
Tissues Epithelial
Muscle
Nerve
Connective
Muscle & Nerve Tissue Very little replacement in adults
Problematic because heart tissue that becomes damaged during a heart attack or brain tissue that becomes damaged during a stroke is not replaced.
Skin Functions:
Protection against UV
Chemicals
Pathogens
Waterproofs the body
Temp regulation - Blood flow to the skin
Vitamin D synthesis
Sensation of touch, temp, and pain
Epidermis Highest level of skin
Dead skin
basal cell skin cancer originates in the stratum basal
stratum basal vulnerable to UV radiation
Has no blood vessels
Dermis Middle level of skin
thick layer below epidermis
blood vessels and nerves
2 kinds of protein fiber
- Collagen fibers provide strength
- Elastin fibers provide strength and flexibility
Elastin is destroyed by age, UV, smoking, resulting in wrinkles
Hypodermis Bottom level of skin
Stratum Corneum Made of dead cells that are full of Keratin, a protein that helps waterproof the cells.
Sebaceous Gland Produce oil, protect skin, attached to hair follicles, can cause infections.
Eccrine Glands Produce sweat that helps the body thermooregulate, found all over body
Apocrine Glands Produce chemical odors, pheromous, found under arm region
Arrector Pili Muscles that move hair
Basal Cell Cancer Most common in light skinned people
Can be treated by cutting off or Freezing
Squamous Skin Cancer 2nd most common type
May metastasize if not removed
Can be difficult to cure
Malignant Melanoma Rarest but most deadly
ABC
A= Asymetric
B= Rough Border
C= Uneven Color
D= Diameter larger than a pencil eraser
1st Degree burn Limited to epidermis
2nd Degree Burn Extends into Dermis
Causes blistering, redness and burn
3rd Degree Burn Destroys skin at burn site, nerves and blood vessels are gone.
Edges are very painful even though burn area has no sensation
Skin grafts are necessary to allow healing of the burned area
Vitamin D Necessary for calcium absorption
Rickets Lack of Vitamin D results in deformed, soft bones
Red blood cells Erythocytes
Made in bone marrow
Live 120 days
White blood Cells Leukocytes
Platelets Thrombocytes
Help with blood clotting
Plasma High levels of protein Albumin
Serum Plasma with the Clotting proteins removed
Erythropoietin Signals the bone marrow to produce more red blood cells
Iron Deficiency Anemia Results from a lack of Dietary Iron
Can be remedied with iron supplements
Hemochromatosis Liver accumulates too much iron
Can cause liver failure
Treated by regular blood draws
Aplastic Anemia Occurs when Red blood marrow is damaged by radiation, chemicals or cancer and stops production
Pernicicious Anemia Occurs when digestive tract can not absorb Vitamin B12.
Treated with oral B12 or injections
Sickle Cell Anemia Results from genetic disorder. Both parents must be carriers
Sickle red blood cells wear out fast and block blood vessels.
Erythrocytes Contain Hemoglobin
Hemoglobin binds to Oxygen and carries it to cells of the body.
Iron is necessary for Hemoglobin to function Correctly.
Bilirubin Old Hemoglobin
Liver pulls it out of blood and turns it into bile
Gall bladder secretes bile into the small intestine.
If the liver stops working, could result in Jaundice.
Leukocytes Neutrophils
Lymphocytes
B Lymphocytes
Killer T Lymphocytes
Helper T lymphocytes
Neutrophils Most common type of White Blood Cell.
Live for 3 days
Use phagocytosis to engulf foreign particles and bacteria
Neutropenia Low levels of neutrophils
Pus Dead Neutrophils
Lymphocytes Second most common type of White Blood Cell
B Lymphocytes Produce Antibodies which protect you from infection
Killer T Lymphocytes Attack Cancer Cells
Attack viruses and kill virus-infected cells
Helper T Lymphocytes Activate B and Killer T lymphocytes
Leukemia Cancer of the Bone Marrow
Uncontrolled production of abnormal White Blood Cells
Leukocytosis A higher than normal white blood cell count
can happen when the body is fighting an infection.
Leukopenia Low white blood cell count
HIV
Hemostasis Blood Clotting, 3 steps: Vascular spasm, Platelet plug, Coagulation
1. Tissue Damage
2. Vascular Spasm-blood vessels squeeze shut as much as they can to reduce blood loss
3.Coagulation
3.1 Prothrombin
Heparin Prevents prothrombin activator from turning prothrombin into thrombin.
Fast acting and is often used medically to stop blood from clotting.
Warfarin (Coumadin) Stops the liver from using vitamin K to make prothrombin.
Takes a longer time to work and is often given to patients at risk of strokes or who have had a stroke in the past.
Hemophilia X-linked disorder, more common in boys.
Treated with injections of factor 8 which these patients cannot make and is necessary in the formation of blood clots
Thromboemolism A blood clot in the wrong place
Thrombus A clot that stays where it formed
Embolus A clot that moves in the blood and is very dangerous
Phlebitis Deep vein thrombosis occurs when blood stagnates in the legs causing clots and pain. if it breaks off and becomes an embolus it is very dangerous.
Blood type Determined by carbohydrate markers found on the surface of blood cells
Type A Blood cells with type A antigens on the surface of their blood cells. Has Anti-B antibodies in their plasma
Type B Blood Cells with Type B antigens on the surface of their blood cells. Has Anti-A antibodies in their plasma.
Type AB Blood cells with both A and B antigens on the surface of their blood cells. Has no antibodies in their plasma.
Type O Blood Cells with no antigens present on the surface of their blood cells. Has both A and B antibodies in their plasma.
RH Factor a blood group antigen possessed by Rh-positive people

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