Cell Bio Cell Signaling

28 terms by christopher_gonzales 

Ready to study?
Start with Flashcards

Create a new folder

Advertisement Upgrade to remove ads

Questions from Dr Groppe's lecture on cell signaling

________________ receptors convert chemical into electrical signals.

Ion channel-linked

What is the conversion of one type of signal into another?

Signal Transduction

What are four types of cell signaling?

Endocrine, Paracrine, Neuronal, and Contact-dependent

__________________ signaling controls nerve-cell production.

Contact-dependent

True or false: The same signal molecule can induce different responses in different target cells.

True

Extracellular signals alter the activity of diverse cell _________ to alter cellular behavior.

proteins

Extracellular signal molecules can bind to ______________ receptors or _____________ receptors and enzymes.

extracellular; intracellular

Nitric oxide (NO) triggers smooth muscle _____________ in a blood-vessel wall.

relaxation

Steroid hormones bind intracellular receptors that act as _________________________ proteins.

gene regulatory

True or false: Gases such as NO are the only signal molecules that can cross the plasma membrane.

False.

The steroid hormone __________ acts by activating a gene regulatory protein.

Cortisol

What are the three basic classes of cell surface receptors?

G-protein-linked, Ion-channel-linked, and Enzyme-linked

Many intracellular signaling proteins act as ___________________.

molecular switches

True or false: All G-protein-linked receptors possess a similar structure.

True

When activated, G-proteins....?

dissociate into two signaling proteins

The G protein alpha-subunit switches itself off by _______________________.

hydrolyzing bound GTP

G proteins couple receptor activation to opening of _______________ K+ channels.

cardiomyocyte

What catalyzes the synthesis of intracellular second-messengers?

Enzymes activated by G-proteins

Cyclic AMP is synthesized by ____________, and degraded by __________________

adenyl cyclase; cyclic AMP phosphodiesterase

Cyclic AMP concentration rises rapidly in response to which extracellular signal?

neurotransmitter serotonin

Receptor tyrosine kinases activate the GTP-binding protein _____.

Ras

_______________ networks integrate information to control complex cell behaviors.

Protein kinase

Activation of a _______________________ directs assembly of an intracellular complex.

receptor tyrosine kinase

True or false: The Ras protein is monomeric and a membrane-linked GTPase.

True

__________ percent of human cancers come from activating mutations in ras genes.

Thirty

________________ activates a MAP-kinase phosphorylation cascade

Ras GTPase

What receptors are associated with cytoplasmic tyrosine kinases?

Cytokine receptors

TGF-beta/BMP receptors activate ___________________ directly at the plasma membrane.

gene regulatory proteins

Please allow access to your computer’s microphone to use Voice Recording.

Having trouble? Click here for help.

We can’t access your microphone!

Click the icon above to update your browser permissions above and try again

Example:

Reload the page to try again!

Reload

Press Cmd-0 to reset your zoom

Press Ctrl-0 to reset your zoom

It looks like your browser might be zoomed in or out. Your browser needs to be zoomed to a normal size to record audio.

Please upgrade Flash or install Chrome
to use Voice Recording.

For more help, see our troubleshooting page.

Your microphone is muted

For help fixing this issue, see this FAQ.

Star this term

You can study starred terms together

NEW! Voice Recording

Create Set