During Griffith's experiments with Streptococcus pneumoniae in mice, material from _____ bacteria transformed _____ bacteria.
heat-killed virulent; living nonvirulent
Monomers for the synthesis of DNA are called _____.
Chargaff found that for DNA _____.
the ratio of A to T is close to 1:1 and the ratio of G to C is close to 1:1
A forms ___ __________ bonds with ________
2 hydrogen, T
G forms ___ ___________ bonds with ____________
3 hydrogen, C
The two sugar-phosphate strands of a DNA molecule are joined to each other through _____
hydrogen bonds between nucleotide bases
Which of the following attributes of DNA is most crucial to its accurate duplication?
its specific base pairing and hydrogen bonding
During the replication of DNA, _____
both strands of a molecule act as templates
The rate of elongation in prokaryotes is _____ the rate in eukaryotes
much faster than
DNA polymerase adds nucleotides to the _____ of the leading strands, and to the _____ of the lagging strands (Okazaki fragments).
3' end; 3' end
What enzyme joins Okazaki fragments?
After the formation of a replication bubble, which of the following is the correct sequence of enzymes used for the synthesis of the lagging DNA strand?
helicases, primase, DNA polymerase, ligase
The removal of the RNA primer and addition of DNA nucleotides to the 3' end of Okazaki fragments in its place is carried out by _____.
DNA polymerase I
Unlike prokaryotic DNA replication, replication of eukaryotic chromosomes _____.
cannot be completed by DNA polymerase
Put the following DNA-containing entities in order according to the amount of DNA found in their genomes.
virus, bacteria, eukaryote
The "beads on a string" seen in interphase chromatin are _____