ABX usage, dosage

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Created by:

iDoRX  on January 27, 2010

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ABX usage, dosage

Amphotericin B deoxycholate dose
0.6-1 mg/kg/day
1/23
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Amphotericin B deoxycholate dose 0.6-1 mg/kg/day
Amphotericin B lipid formulation 3-5 mg/kg/day
fluconazole does not cover C. krusei, Aspergillus, other molds, Candida glabrata (susceptible)
fluconazole for mucosal candidiasis 100-400 mg/day, 150mg for vagina
fluconazole for systemic candidiasis 400-800+mg q24
fluconazole for cryptococcal meningitis 400mg q24h
itraconazole for aspergillus 200mg po BID
voriconazole for invasive aspergillosis, candidiasis 6mg/kg IVq12h x 24h, then 4mg/kg IVq12h or 200+mg po q12
posaconazole for prophylaxis 200mg po TID
posaconazole for oropharyngeal candidiasis 100mg po BID, then 100mg qd, with fatty meal
caspofungin dosing 70mg day1, then 50mg per day
micafungin for esophageal candidiasis 150mg/day
micafungin for hematopoetic stem cell transplantation 50mg/day
micafungin for candidemia albicans 100mg/day
anidulafungin for candidemia 200mg day1, then 100mg per day
anidulafungin for esophageal candidiasis 100mg day1, then 50mg per day
flucytosine dosing 37.5mg/kg q6h
clotrimazole troches for oropharyngeal candidiasis 10mg 5 times a day
fluconazole for oropharyngeal candidiasis 100-400mg/day
fluconazole for esophageal candidiasis 200-400mg/d
amphotericinB for esophageal candidiasis 0.3-0.7 mg/kg/d
gold standard for invasive candidiasis txtment echinocandin, then amphotericin B
gold standard for invasive aspergillosis voriconazole, then amphotericin B

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