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All the online MC and the difficult ones from the book

Which of the following is a true statement?
A) In a DNA molecule, the amount of thymine equals the amount of cytosine.
B) The DNA molecule in bacteria is a single strand.
C) The amount of guanine in a DNA molecule varies from species to species.
D) Complementary base pairing means that a purine is always paired with another purine.
E) Watson and Crick discovered the function of DNA.

C

In a DNA molecule, the bases are covalently bonded to each other.
A) True.
B) False.

B

During DNA replication
A) only one strand of the parent DNA is copied.
B) neither strand of parent DNA appears in daughter DNA.
C) DNA replication is considered conservative.
D) the strands of parent DNA are unwound.
E) complementary nucleotides are positioned by the enzyme helicase.

D

Which of the following is not true regarding the structure of RNA?
A) RNA contains the same four nucleotide bases as DNA.
B) RNA contains ribose.
C) RNA is single stranded.
D) RNA in general is a helper to DNA.
E) There are different types of RNA, each with a different function.

A

The function of messenger RNA (mRNA) is to transfer amino acids to the ribosomes during protein synthesis.
A) True.
B) False.

A

Ribosomal RNA
A) covalently binds amino acids.
B) contains an anticodon.
C) is produced in the nucleolus of the nucleus.
D) assists in DNA replication.
E) has no known function in the cell.

C

In __________ every three bases is a/an _____________ that codes for a/an _____________.
A) DNA; anticodon; mRNA
B) mRNA; codon; amino acid
C) tRNA; codon; protein
D) mRNA; triplet; amino acid
E) tRNA; anticodon; codon

B

The genetic code varies from species to species.
A) True.
B) False.

B

Which is a true statement?
A) For mRNA synthesis to occur, DNA polymerase must bind to a promoter region on the DNA.
B) RNA polymerase uses mRNA to synthesize more copies of mRNA.
C) Introns are converted into triplets during transcription.
D) Transcription is the process of protein synthesis.
E) Translation occurs in the cytoplasm.

E

mRNA processing
A) is the degradation of old RNA.
B) occurs after transcription.
C) occurs at the ribosomes.
D) converts introns into primary RNA.
E) removes exons from mature RNA.

B

During translation, the anticodon of tRNA pairs with
A) an amino acid.
B) another tRNA molecule.
C) bases in mRNA.
D) ribosomal RNA.
E) a DNA triplet.

C

There is at least one transfer (tRNA) molecule for each of the twenty amino acids.
A) True.
B) False.

A

Which of the following is not a part of the process of translation?
A) initiator tRNA binding to the ribosome
B) removal of introns from mRNA
C) mRNA binding to the ribosome
D) joining large and small ribosomal subunits
E) chain termination at a stop codon

B

The removal of a nucleotide from a gene in the DNA leads to a _______________.
A) point mutation
B) mutagen
C) transposon
D) frameshift mutation
E) none of the above

D

Which of the following is matched correctly?
A) DNA fingerprinting--requires restriction enzymes
B) polymerase chain reaction--makes use of the noncoding sections of DNA
C) DNA ligase--makes many copies of a segment of DNA
D) point mutation--addition of a nucleotide base to DNA
E) recombinant DNA--contains DNA from two or more different sources.

E

If one strand of DNA has the following sequence: CGGCTAATCGCC, what would the sequence of the complimentary strand be?
A) CGGCTAATCGCC
B) GCCGATTAGCGG
C) CGGCUAAUCGCC
D) CGGCTUUTFCGG
E) can't be determined

B

If the codon of an mRNA strand is UGC, the anticodon of the tRNA would be ___________ and the amino acid, ____________, will be added to the growing peptide chain.
A) UGC; cysteine
B) ACG; arginine
C) TCG; unknown
D) AGC; serine
E) ACG; threonine

E

A tiny spot of blood was found on a glove at a crime scene. What method of DNA technology would you use to make more copies of the DNA sample left at the scene?
A) DNA fingerprinting
B) recombinant DNA
C) mutagenesis
D) PCR
E) transgenics

D

Gene "pharming" involves which of the following DNA technologies?
A) DNA fingerprinting
B) recombinant DNA
C) mutagenesis
D) PCR
E) transgenics

E

The completion of the Human Genome Project allowed us to sequence all of the human genome and to know the function of all of the genes.
A) True
B) False

B

Which of the following is not true regarding a karyotype?
A) It arranges chromosomes into pairs based on size, shape, and banding pattern.
B) The procedure can be done on fetal cells.
C) It can be done using any cell in the body.
D) It is a means of diagnosing a chromosomal abnormality.
E) It can be done using any nucleated cell in the body.

C

Chorionic villi sampling (CVS) is a much safer procedure than amniocentesis because CVS is done later in pregnancy.
A) True.
B) False.

B

An exchange of chromosomal segments between two nonhomologous chromosomes is a/an
A) deletion.
B) reciprocation.
C) duplication.
D) translocation.
E) inversion.

D

In a duplication,
A) a person has more than two alleles for a certain trait.
B) crossing-over between sister chromatids has occurred twice.
C) a particular segment is missing on one chromosome.
D) a chromosomal segment is turned 180o.
E) chromosomal segments are exchanged between two nonhomologous chromosomes.

A

In an autosomal dominant genetic disorder, if both parents have the disorder, what is the chance that their sons will have the disorder?
A) O%
B) 25%
C) 50%
D) 100%
E) Impossible to determine from this information alone.

E

X-linked recessive disorders often pass from grandfather to granddaughter.
A) True.
B) False.

B

A male has a particular X-linked recessive genetic disorder. His partner is normal, but her father had the disorder. What is the chance that their sons will have the disorder?
A) 0%
B) 25%
C) 50%
D) 100%
E) Impossible to determine from the information given.

C

Phenylketonuria (PKU) is an autosomal recessive disorder. If a woman who does not have PKU gives birth to a child who has PKU, which of the following men, based on this information alone, could not be the father of the child?
A) a man who has PKU.
B) a man who does not have PKU, none of his siblings or cousins have it, and there was no PKU in his family for six generations before him.
C) a man who does not have PKU but whose mother had PKU.
D) a man who does not have PKU but whose maternal grandmother and paternal grandfather had PKU.
E) Any of these men could be the father of the child.

B

A boy is color blind. Which of the following is certain?
A) His brothers are also color blind.
B) His father is color blind.
C) His mother is color blind.
D) His sisters are carriers of color blindness.
E) His brother has at least a 50% chance of being color blind.

E

Two parents are affected with a genetic disorder. They produce an unaffected child. The disorder is likely transmitted as an autosomal dominant trait.
A) True.
B) False.

A

An abnormality in DNA sequence used in a test to determine an abnormal allele is called a
A) histone.
B) DNA chip.
C) genetic marker.
D) DNA probe.
E) restriction fragment.

D

The only two methods by which fetal cells can be obtained for testing are amniocentesis and chorionic villi sampling.
A) False.
B) True.

A

A genetic profile
A) can detect mutations in a person's genes.
B) is only obtained by taking a blood sample from an individual.
C) can not be done with accuracy with today's technology.
D) is illegal in the United States.
E) is not helpful in determining mutations associated with disease risk.

A

The insertion of genetic material into human cells for treatment of a disorder is called
A) translocation.
B) amniocentesis.
C) CVS.
D) gene therapy.
E) deletion.

D

What is the difference between ex vivo gene therapy and in vivo gene therapy?
A) in ex vivo gene therapy, the gene is delivered directly into the body.
B) in in vivo gene therapy, the gene is inserted into cells that have been removed and are returned to the body after the manipulation.
C) in ex vivo gene therapy, the gene is inserted into the cells that have been removed and are returned to the body after the manipulation.
D) in vivo and ex vivo gene therapy are the same procedures.
E) ex vivo gene therapy uses bone marrow stem cells and in vivo does not.

C

Ultrasound images do all the following except?
A) transmit high frequency sound waves while scanning the mother's abdomen
B) help doctors evaluate fetal anatomy
C) show a picture of the fetus inside the uterus
D) determine the baby's age and size
E) determine karyotype of the fetus

E

Some genetic mutations can be determined by testing for proteins.
A) True
B) False

A

An autosomal recessive disorder that occurs among all ethnic groups, in which chloride ions fail to pass through a plasma membrane channel protein in the cells and leads these patients to develop thick mucus in their bronchial tubes and pancreatic ducts is ________.
A) sickle cell disease
B) methemoglobinemia
C) cystic fibrosis
D) alkaptonuria
E) marfan syndrome

C

An autosomal recessive disorder in which erythrocytes are not biconcave disks, but are irregular in shape is called __________.
A) sickle cell disease
B) methemoglobinemia
C) cystic fibrosis
D) alkaptonuria
E) marfan syndrome

A

These disorders are present only in males and are passed from father to all sons, but, not to daughters.
A) X-linked disorders
B) X-linked recessive disorders
C) X-linked dominant disorders
D) Y-linked disorders
E) autosomal dominant disorders

D

Which of the following is NOT a feature of eukaryotic DNA replication?
A) Replication bubbles spread in two directions
B) A new strand is synthesized using the old one as a template
C) Complementary base paring determines which nucleotides should be added to a new strand
D) Each chromosome has one origin of replication

D

Which of the following statements about the genetic code is NOT true?
A) The genetic code is almost universal
B) The genetic code is a doublet code
C) Multiple codons may encode the same amino acid
D) Some special codons mean "stop"

B

The application of computer techniques to analyze the genome is called
A) proteomics
B) Bioinformatics
C) Genomics
D) Genetic code

C

Which of the following is NOT useful in creating recombinant DNA?
A) restriction endonuclease
B) DNA ligase
C) RNA polymerase
D) Plasmid

C

The major advantage of CVS over amniocentesis is that it
A) Allows karyotyping to be done earlier
B) Produces karyotypes with better images of chromosomes
C) Carries a lower risk of spontaneous abortion
D) Produces a sample that is not contaminated by cells from the mother

A

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