Science Focus 10 - Biology Set 1: Intro Definitions

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Alberta Science Focus 10 - Biology (Published 2004) Unit 3 Cycling of Matter in Living Systems Chapter 7 The Basis of Life Chapter 8 Dynamic Cells Chapter 9 From Cell to Organism: Focus on Plants

Aristotle (384 BC - 322 BC)

a Greek philosopher whose theory of abiogenesis or spontaneous generation was accepted for over 2000 years.

Abiogenesis

living things could arise from non-living Matter.

Aristotle Method

created his theories on the origin of life based on his many observations, however, he did not conduct any scientific experiments to test his ideas.

Francesco Redi (1626 - 1697)

Italian physician who used controlled scientific experiments to refute the theory of spontaneous generation

Louis Pasteur (1822 - 1895)

French scientist who finally settled the continued debate of the theory of abiogenesis.

Biogenesis

living things could only arise from other living organisms.

Cell

smallest functional unit of life

Cell Theory

explains and defines the boundary between the living and non-living.

Robert Hooke (1635 - 1703)

looked at cork with a compound light microscope (30X magnification) and was the first to see and name "cells".

Antony van Leeuwenhoek (1632 - 1723)

Dutch linen merchant who first described single-celled microorganisms. He called his sightings "animalcules"

Matthias Schleiden (1804 - 1881) and Theodor Schwann (1810 - 1882)

German scientists who studied cells in hundreds of plants and whose research contributed to the cell theory, stating that "all organisms are made of cells "

Rudolf Vichow

German physician who made microscopic observations of cells dividing and completed the cell theory still accepted today.

Rudolf Virchow

the first scientist to link illnesses to malfunctioning cells

The Cell Theory

1. All organisms are composed of one or more cells.
2. The cell is the smallest functional unit of life.
3. All cells are produced from other cells.

Light Microscopes

use to view objects illuminated by visible light

Simple microscope

used only one lens (similar to a magnifying glass)

Compound microscope

uses two or more lenses placed one on top of the other

Electron microscope

specimens are illuminated with a beam of electrons instead of a beam of light. It magnifies up to 1.2 million times

Electron micrograph

the photograph of the image produced by an electron microscope

TEM

transmission electron microscope

SEM

scanning electron microscope

CLSM

confocal laser scanning microscope

STM

scanning tunnelling microscope

Genes

sections of DNA that direct the activities of our cells
- changes in the gene can cause improper cell function
eg. Sickle cell anemia

DNA

carries all genetic information of the organism, coiled to form chromosomes, found in the nucleus of every cell

4 Bases of DNA

Adenine pairs with Thymine, Cytosine pairs with Guanine

Genetic Code

made up of thousands of pairs of DNA bases

Q: Fill in the missing bases on this piece of DNA

A __ T__ G__ C__

Gene Sequencing

mapping the order of all of a gene's bases

Human Genome Project (HGP)

an international project to sequence all 30000 to 40,000 human genes

Gene Therapy

human gene is "corrected" to help cure a disorder or cancer

Cancer

most cancers are caused by gene damage, some of which create mutations

Mutations

changes in the base sequence of a gene

Virus

non-cellular structure made of a piece of genetic material enclosed in a protein coat.
In order to reproduce, a virus must infect a cell

Prion

a protein that can convert into a harmful particle which can reproduce in living tissue

Cell culture

isolated cells are given nutrients and their growth and division are studied

Cell lines

the generations of cells produced from a culture; can be grown indefinitely in a lab

Stem cells

"blank slate" cells that divide to produce all other types of specialized cells

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