classic lab findings II

Created by mattd05j 

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tabes dorsalis (tertiary syphilis)

degeneration of dorsal column nerves

Parkinson's disease

depigmentation of neurons in substantia nigra

Curschmanns' spirals (bronchial asthma; can result in whorled mucous plugs)

Desquamated epithelium casts in sputum

Call-Exner bodies (granulosa-thecha cell tumor of the ovary)

Disarrayed granulosa cells in eosinophilic fluid

Koliocytes (HPV: predisposes to cervical cancer)

Dysplastic squamous cervical cells with nuclear enlargement and hyperchromasia

Owl's eye appearance of CMV

enlarged cells with intranuclear inclusion bodies

Orphan annie nuclei (papillary carcinoma of the thyroid)

enlarged thyroid cells with ground glass nuclei

Mallory bodies

eosinophilic cytoplasmic inclusion in liver cell

Lewy body

Eosinophilic cytoplasmic inclusion in nerve cell

Councilman body (toxic or viral hepatitis, often yellow fever)

Eosinophilic globule in liver

Rabies virus (Lyssavirus)

Eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells

Senile plaques

Extracellular amyloid deposition in gray matter of brain

Reed-sternberg cells (Hodgkin's lymphoma)

Giant B cells with bilobed nuclei with prominent inclusions

schiller-duval bodies

glomerulus like structure surrounding vessel in germ cells (yolk sac tumor)

Beta-thalassemia, sickle cell anemia

Hair on end (crew-cut) appearance on X-ray

Chriocarcinoma, hydatiform mole

hCG elevated

Aschoff bodies

Heart nodules (inflammatory)

Infectious mononucleosis

Heterophile antibodies

Bronchial asthma

Hexagonal, double-pointed, needle-like crystals in bronchial secretions

DVT, pulmonary embolism, DIC

High levels of D-dimers

Interstitial fibrosis

Honeycomb lung on x-ray

Megaloblastic anemia (B12, folate deficiency)

Hypersegmented neutrophils

Iron deficiency anemia, lead poisoning, thalassemia (HbF sometimes present)

Hypochromic, microcytic anemia

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