pharmacology nclex review antibiotics

39 terms by shamilton82 

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aminoglycosides

gentamycin, neomycin, streptomycin, tobimycin

aminoglycosides

inhibit synthesis of gram-negative bacteria

aminoglycosides

otoxicity, nephrotoxicity, n/v/d

aminoglycosides

check hearing, check renal fx, 7-10 days, FLUIDS!

cephalosporins

ceclor (cefaclor), ancef (cephazolin), keflex (cephalexin), rocephin (ceftriaxone), mefoxin (cefoxitin)

cephalosporins

inhibit synthesis of bacterial cell wall

cephalosporins

bone marrow depression, superinfections, rash

cephalosporins

***take with food - GI upset***, cross allergy with penicillin, avoid alcohol, obtain c&s

floroquinolones

cipro (ciprofloxin)

floroquinolones

interferes with DNA replication in gram-negative bacteria

floroquinolones

e. coli, psuedomonas, s. aureus, anthrax

floroquinolones

diarrhea, decreases WBC, hct, elevated AST/ALT, elevated alk phos

floroquinolones

C&S, FLUIDS, 1 hr ac or 2 hr pc, not with antacids or iron

macrolide

erythromycin, cleomycin (clindamycin) - different mycin!

macrolide

binds to cell membrane and changes protein fx

macrolide

acute infections, acne, URI

macrolide

diarrhea, confusion, hepatoxicity, superinfection, increases effectiveness of coumadin

macrolide

1 hr ac or 2-3 hr pc, monitor LFT, take with water- not juice

penicillins

amoxicil (amoxicillin), ampicillin, augmentin (amox/clavunalnate) -"-cillin"

penicillins

inhibit cell wall synthesis

penicillins

moderate to severe infection, lymes

penicillins

stomatitis (entire GI), allergy, renal/hepatic dmage

penicillins

check for hypersensitivity (multiple exposures), 1-2 hr ac or 2-3 pc, cross allergy with cephalosporin, liver/kidney function

sulfonamides

gantrisin (acetyl sulfisoxasole), bactrim (cotrimoxazole), azulfinide (sulfasalazine)

sulfonamides

antagonize essential components of folic acid synthesis

sulfonamides

ulcerative colitis, Crohn's disease, otitis media, UTIs

sulfonamides

peripheral neuropathy, crystalluria, photosensitivity, GI upset, stomatitis

sulfonamides

***take with food***, encourage fluids, good mouth care

tetracyclines

inhibit protein synthesis

tetracyclines

vibramtxin (doxycycline), panmycin (tetracycline)

tetracyclines

infections, acne, prophylaxis for opthalmia neonatorum

tetracyclines

discolors primary teeth, glossitis, rash, phototoxic

tetracyclines

1-2 r ac, 2-3 hr pc, not with antacids/milk/iron, sunblock - avoid sun, note expiration date (toxic), monitor renal function

furadantin

nitrofuran

furadantin

anti-infective, UTI specific

furadantin

asthma attack, give with cranberry juice, monitor pulmonary status (risk for asthma attack)

pyridium

phenoazopyridine

pyridium

urinary tract analgesic, UTI

pyridium

turns urine orange, headache, vertigo

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