Antivirals

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Created by:

iDoRX  on February 24, 2010

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Antivirals

Neuraminidase inhibitors
oseltamivir (Tamiflu), zanamivir (inhaled), carbocyclin
1/18
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Definitions

Neuraminidase inhibitors oseltamivir (Tamiflu), zanamivir (inhaled), carbocyclin
Influenza A amantadine (Symmetrel), rimantidine
Guanosine analogs acyclovir (Zovirax), valacyclovir, famcyclovir, ganciclovir (Cytovene), valganciclovir,
Acyclic Nucleoside Phosphates (cytidine analogs) adefovir, cidofovir
Ganciclovir key words cytomegalovirus, UL97 gene, intraocular implant, neutropenia, thrombocytopenia, increased SCr
valganciclovir key words cytomegalovirus, AIDS/BMT pts, marrow depression, granulocytopenia, testicular injury
pyrophosphate analog foscarnet (Foscavir)
foscarnet key words CMV retinitis in AIDS pts, ADR renal impairment, fever, NVD, hypocalcemia
Antisense protein synthesis inhibitor fomivirsen
fomivirsen key words early region of CMV mRNA, intra-vitreal administration
Anti-hepatitis agents adifovir, cidofovir, ribavirin, lamivudine, IFN-alpha/beta/gamma
Nucleoside reverse transcriptase inhibitors (NRTIs) zidovudine (azidothymidine, AZT, Retrovir), tenofovir (TDF, Viread)
other NRTIs 2,3-dideoxyinsoine (didanosine, DDI, Videx), stavudine (D4T, Zerit), lamivudine (3TC), emtricibine, abacavir (ABC, Ziagen)
non-nucleoside reverse transcriptase inhibitors (NNRT) nevirapine (Viramune), Efavirenz (Sustiva), delaviridine, loviride, etravirine
protease inhibitors ritonavir (Norvir), nelfinavir (Viracept), saquinavir, indinavir, amprenavir, lopinavir, trapinavir, darunovir,
Fusion inhibitors enfuvirtide (Fuzeon, T-20)
Chemokine (CCR5) inhibitors maraviroc (Selzentry)
Integrase inhibitors raltegavir (Isentress), elvitegravir

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