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5 Written questions

5 Matching questions

  1. nucleosome
  2. Leading strand
  3. replication fork
  4. repetitive DNA
  5. x-ray crystallography
  1. a The new complementary DNA strand synthesized continuously along the template strand toward the replication fork in the mandatory 5'?3' direction.
  2. b The basic, bead-like unit of DNA packing in eukaryotes, consisting of a segment of DNA wound around a protein core composed of two copies of each of four types of histone.
  3. c A technique that depends on the diffraction of an X-ray beam by the individual atoms of a crystallized molecule to study the three-dimensional structure of the molecule.
  4. d A Y-shaped region on a replicating DNA molecule where the parental strands are being unwound and new strands are growing.
  5. e Nucleotide sequences, usually noncoding, that are present in many copies in a eukaryotic genome. The repeated units may be short and arranged tandemly (in series) or long and dispersed in the genome.

5 Multiple choice questions

  1. The tandemly repetitive DNA at the end of a eukaryotic chromosome's DNA molecule that protects the organism's genes from being eroded during successive rounds of replication. See also repetitive DNA.
  2. A discontinuously synthesized DNA strand that elongates by means of Okazaki fragments, each synthesized in a 5'3' direction away from the replication fork.
  3. A protein that breaks, swivels, and rejoins DNA strands. During DNA replication, topoisomerase helps to relieve strain in the double helix ahead of the replication fork.
  4. A linking enzyme essential for DNA replication; catalyzes the covalent bonding of the 3' end of one DNA fragment (such as an Okazaki fragment) to the 5' end of another DNA fragment (such as a growing DNA chain).
  5. A dense region of DNA in a prokaryotic cell.

5 True/False questions

  1. deoxyriboseAn enzyme that catalyzes the lengthening of telomeres in eukaryotic germ cells.


  2. semiconservative modelType of DNA replication in which the replicated double helix consists of one old strand, derived from the old molecule, and one newly made strand.


  3. heterochromatinEukaryotic chromatin that remains highly compacted during interphase and is generally not transcribed.


  4. euchromatinThe complex of DNA and proteins that makes up a eukaryotic chromosome. When the cell is not dividing, chromatin exists in its dispersed form, as a mass of very long, thin fibers that are not visible with a light microscope.


  5. Mismatch repairThe cellular process that uses specific enzymes to remove and replace incorrectly paired nucleotides.


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