What are secondary bile acids?
Deoxycolic acid and Deoxychenocholic acid
One OH group is missing from both
When are bile acids released?
Released into intestine during a meal - helps digestion of dietary lipids
What are the two set of bile salts that are formed from cholesterol?
Two sets of bile salts are formed from cholesterol:
2. Cholate - Salt Form
What are conjugated bile salts?
They are formed in the liver and secreted in the bile. They are powerful detergents that break down fat globules, enabling them to be digested.
What amino acids are used to make conjugated bile salts?
Taurocholic Acid - Taurine
Glycocholis acid - Glycine
What is the functional advantage of conjugated bile salts?
They make better detergents.
Primary salts break down the FA molecules that easy to solubilize.
The secondary salts break down the FA's that are harder to solubilize.
The FA fats that are the hardest to solubilized are solubilized by conjugated bile salts.