histology (chapter 5)

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fgc2c  on March 9, 2010

Subjects:

Anatomy and Physiology I

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histology- chapter 5 (saladin)

Classes:

Anatomy and Physiology I- Dr. Hughes

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histology (chapter 5)

tissue
a group of similar cells and their products that carry out a specific function (structural or physiological)
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Terms

Definitions

tissue a group of similar cells and their products that carry out a specific function (structural or physiological)
four types of tissue epithelia, connective, nervous, and muscular
histology the study of tissue also called microscopic anatomy
composition of matrix fibrous proteins and a clear gel (ground substance,tissue fluid, extracellular fluid (ECF), interstitial fluid, or tissue gel) ( water, gases, minerals, nutrients, wastes and other chemicals)
composition of tissue cells, matrix
epithelial tissue one or more layers of closely adhering cells. It forms a flat sheet with the upper surface exposed to the environment or an internal body cavity. it sits on the basement membrane (nerve and blood supply)
examples of epithelial tissue epidermis, inner lining of digestive tract and liver and other glands
connective tissue tissue with more matrix than cell volume. consists of widely spaced cells separated by fibers and ground substance. most abundant and variable tissue type FUNCTION: (support, bind together and protect organs) connects organs to each other, storage of energy and heat production, movement and transport of materials
examples of connective tissue tendons, ligaments, cartilage and bone, blood
nervous tissue contains cells specialized for rapid transmission of coded information toother cells
examples of nervous tissue brain, spinal cord, and nerves
muscular tissue tissue composed of elongated cells specialized for contraction
examples of muscular tissue skeletal muscles, heart(cardiac muscle), walls of viscera (smooth muscle)
primary germ layers Three layers of embryonic tissue from which all primary tissues and body organs are derived; includes ectoderm, mesoderm and endoderm
ectoderm outer layer & gives rise to the epidermis and nervous system
mesoderm between ectoderm and endoderm. forms mesenchyme
endoderm inner layer gives rise to the mucous membranes of the digestive (GI tract ) and respiratory tracts and to the digestive glands
mesenchyme (mesoderm) composed of fibroblast it gives rise to muscle, bone and blood among other tissues
fibroblast collagen (protein) , branching cells used in the ground substance
how many cells does the body contain? 200 different cell types
basement membrane thin layer of collagen and adhesive proteins. anchors epithelium to underlying connective tissue
two types of epithelial tissue simple and stratified
types of simple epithelial tissue squamous (thin) , cubodial(square), columnar(tall) and pseudostratified columnar(short + long)
fibrous connective tissue is the most diverse type of connective tissue. it is also called fibroconnective tissue or connective tissue proper
components of fibrous connective tissue cells, fibers and ground substance
cells in fibrous connective tissue fibroblast, macrophages, leukocytes(white blood cells), plasma cells, mast cells, and adipocytes
fibroblast they produce the fibers and ground subtance that form the matrix of the tissue
macrophages they destroy bacteria. dead or dying cells of our own body. - they activate the immune system when they sense foreign matter (antigens) -they arise from Monocytes (white blood cells)
leukocytes (WBC) most of them are neutrophils- which wonder about attacking bacteria. - lymphocytes- dense patches of tiny white blood cells on the mucous membrane that react against bacteria, toxins and other foreign agents.
plasma cells -lymphocytes that turn into plasma cells when they detect foreign agents. they make antibodies (disease fighting proteins). - plasma cells are only seen in the walls of the intestines and in inflamed tissue
mast cells found alongside blood vessels and they secrete 2 types of chemical. - heparin- inhibits blood clotting - histamine- increases blood flow by dilating blood vessels
adipocytes they are called adipose tissue when adipocytes dominate an area. Filled mainly by a globule of triglycerides (fat molecules)
fibers in a fibrous connective tissue collagenous fibers, reticular fibers and elastic fibers.
collagenous fibers - made of collagen- the most abundant of the body's proteins (25% of body proteins) -they are tough and flexible and resist stretching. - name: white fibers -Found: ligaments, tendons and the deep layer of the skin (dermis). also in the matrix of cartilage and bones
reticular fibers thin collagen fibers coated with glycoprotein. - they form a spongylike framework for organs like spleen and lymph nodes
Elastic fibers made of protein called elastin. - they have a coiled structures that allows it to strech and recoil like a rubber band. -found: skin, lungs and arteries. Name : yellow fibers
ground substance of CT usually has a gelatinous to rubbery consistency that absorbs compressive forces and slows the spread of pathogens. consistency resulting from three classes of large molecules : glycosaminoglycans, proteoglycans, and adhesive glycoproteins
glycosaminoglycans regulate water and electrolyte balance -most abundant GAG is chondroitin sulfate- abundant in blood vessels and bones is responsible for the stiffness of cartilage. -Ex: heparin and hyaluronic acid (lubricant in joints and the jellylike body of the eyeball)
proteoglycans create a strong bond between extracellular macromolecules to hold tissues together and slows the spread of pathogenic organism through the tissues.
adhesive glycoprotein binds plasma membrane to collagen or proteoglycans outside of the cells also mark pathway for cell migration
adipose tissue (CT)also called fat- is tissue which adipoctes are the dominant cell type. -- Functions: provides thermal insulation, anchors, cushions such organs like eyeballs and kidneys, provides contours to the female breasts and hips. -women have for fat them men do and helps meet the calorie intake of nursing. two types of fat: white and brown
white fat most adipose tissue.
Brown fat heat generating fat and accounts for up to 6% of an infants body weight. color( abundance of blood vessels and certain enzyme in the mitochondria) - the don't make ATP the energy is only used for heat. - hibernating animal have brown fat in preparation for winter
cartilage (CT) supportive connective tissue with a flexible rubbery matrix. the matrix is rich in chondroitin sulfate and collage fibers. (damaged cartilage slow to recover - Found: tip of nose, the larynx and the external ear - three types: hyaline, elastic and fibrocartilage
steps of formation of cartilage 1. chondroblast- secrete matrix and surround themselves until they are trapped in 2.lacunae(cavity) - once trapped in lacunae they are called 3.chondrocytes- make cartilages
hyaline cartilage clear, glassy appearance. usually invisible fineness of its collagen fibers. Surrounded by perichondrium - a dense irregular connective tissue
elastic cartilage elastic fibers. - It has perichondrium. - Ex: external ear shape
fibrocartilage readily visible bundles of collagenzZX
bone tissue osseous tissue ---> 2 types : spongy bone and compact bone
spongy bone fills the head of long bones and forms the middle layer of flat bone Found: sternum
compact bone no spaces visible, it also covers spongy bone

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