Measurement of serum levels of which of the following immunoglobulins can serve as a screening test for multiple allergies?
To which of the following classes do the antibodies that cause hemolytic disease of the newborn belong?
It is important to note that when an infant is born, levels of specific antibody of the following class are used to indicate neonatal infection:
Antibody class and antibody subclass are determined by major physiochemical differences and antigenic variation found primarily in the:
constant region of heavy chain
Which of the following immunoglobulin classes is associated with a secretory component (transport piece)?
The immunoglobulin class typically found to be present in saliva, tears and other secretions is:
The key structural difference that distinguishes immunoglobulin subclasses is the:
the sequence of the constant regions
Which of the following immunoglobulins is present in the highest concentration in normal human serum?
Which of the following statements about immunoglobulins is true?
IgA class exists as serum and secretory molecules
After a penicillin injection, a patient rapidly develops respiratory distress, vomiting and hives. This reaction is primarily mediated by:
In immunofixation electrophoresis:
The antigen is electrophoresed and then monospecific antisera is reacted with it
Which of the following is the "membrane attack complex" of complement activation?
C5b, C6, C7, C8, C9
A single, reliable screening test for detecting neonatal infection in the absence of clinical signs is:
quantitative serum IgM determination
Initiation of the activation mechanism of the alternative complement pathway differs from that of the classical pathway in that:
antigen-antibody complexes containing IgA or IgE may initiate activation.
The component associated only with the alternative pathway of complement activation is:
properdin factor B
Potent chemotactic activity is associated with which of the following components of the complement system:
which of the following has been associated with patients who have homozygous C3 deficiency?
a lifelong history of life-threatening infections
Hereditary deficiency of early complement components (C1, C4 and C2) is associated with:
lupus erythematosus like syndrome
Hereditary deficiency of late complement components (C5, C6, C7, or C8) can be associated with which of the following conditions?
a systemic gonococcal infection if exposed