5 Written Questions
5 Matching Questions
- How does plasmodium replicate in humans
- Why is Plasmodium not as prevalent in temperate regions and developed countries?
- Treatment of malaria - problems?
- The five species cause human malaria
- What does P. falciparum do when it infects RBCs
- a Chloroquine, Quinine, Mefloquine, Artemisinin. Drug resistance has developed for these drugs - Chloroquine sucks and Artemisinin is the best, but drug resistance to everything is a problem.
- b asexual schizogony
- c The infected RBCs bind to epithelium causes knobs and rosettes, and ruins clearance in liver and spleen
- d Easier to control vector in temperature regions and in developed countries there is more money and more advanced infrastructure.
- e 1. Plasmodium falciparum 2. Plasmodium vivax 3. Plasmodium malariae 4. Plasmodium ovale 5. Plasmodium knowlesi
5 Multiple Choice Questions
- children under 5 years old
- Found in plasmodium apicomplexans. A pigment they produce as a result of hemoglobin breakdown.
- P. malariae
- Quartan malaria w/ 72 hr recurring fevers. 7% of cases. ZOONOSIS only in monkeys. Invades old RBCs. Doesn't go dormant, but can exist at really small levels up to 53 years.
- 1. Anemia arising from RBC destruction (merozoites released) 2. Host inflammatory response (overproduction of cytokines, fevers and chills)
5 True/False Questions
Invades any RBC → 72 hr recurring fevers
7% of malaria cases → P. vivax
John went backpacking in Asia and South America 8 years ago, and now he has malaria? How? → P. vivax can relapse after up to 8 years, fight it or treat it. Hypnozoite stage in liver is dormant stage.
Hypnozoite stage is present in → P. vivax and P. ovale
Intermediate host of plasmodium is → human