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5 Written questions

5 Matching questions

  1. Two major factors of plasmodium pathogenesis
  2. Does plasmodium have antigenic variation?
  3. List the different species of mosquitoes that can harbor malaria and what region
  4. Hemozoin
  5. 2 main factors for resistance to Plasmodium
  1. a Africa - Anopheles gambiae / Asia - Anopheles stephensi / South America - Anopheles darlingi
  2. b 1. Anemia arising from RBC destruction (merozoites released) 2. Host inflammatory response (overproduction of cytokines, fevers and chills)
  3. c Found in plasmodium apicomplexans. A pigment they produce as a result of hemoglobin breakdown.
  4. d Yep
  5. e 1. Duffy Blood group in west africans protects against p. vivax 2. Sickle cell trait - the heterozygous individuals. Selected for in African ancestries.

5 Multiple choice questions

  1. heteroxenous - mosquito and hman.
  2. P. falciparum
  3. mosquito
  4. Easier to control vector in temperature regions and in developed countries there is more money and more advanced infrastructure.
  5. 1. Plasmodium falciparum 2. Plasmodium vivax 3. Plasmodium malariae 4. Plasmodium ovale 5. Plasmodium knowlesi

5 True/False questions

  1. Treatment of malaria - problems?Chloroquine, Quinine, Mefloquine, Artemisinin. Drug resistance has developed for these drugs - Chloroquine sucks and Artemisinin is the best, but drug resistance to everything is a problem.


  2. John went backpacking in Asia and South America 8 years ago, and now he has malaria? How?P. vivax


  3. Why are some people in Africa resistant to Malaria?P. vivax, invades young RBC's using a single receptor. The DUFFY BLOOD GROUPS or DUFFY ANTIGENs, makes them resistant . Fy=resistant. Fy^a or Fy^b = susceptible.


  4. Benign Tertian Malaria48 hr recurring fevers, More drawn out. P. falciparum


  5. Main way to eliminate malariaKilling vector or preventing vector contact - insecticides, larvicides, bed nets


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