← Plasmodium Test
5 Written Questions
5 Matching Questions
- Plasmodium is vectored by
- What is the problem with trying to treat infected individuals with malaria? Can you eradicate the disease in this way?
- Can a baby catch malaria from mom?
- Antigenic variation in plasmodium
- Life cycle of plasmodium in mosquito
- a After the ring stage trophozoites comes out of liver and produces all the gametocytes, the mosquito bites and ingests the gametocytes from the blood. 1. Macrogamete and microgamete form zygote 2. Ookinete develops and crosses midgut epithelium 3 Ookinete to oocyst 4. Oocyst gives rise to sporozoites via sporogony and the sporozoites go to salivary gland to be injected into host.
- b ~50 var genes, only one expressed at a time. var switching can lead to recrudescence.
- c mosquitoes of the genus Anopheles
- d There will always be asymptomatic carriers
- e No, but sticky RBCs cause low birth weight and thus stillbirth
5 Multiple Choice Questions
- P. malariae
- P. vivax, invades young RBC's using a single receptor. The DUFFY BLOOD GROUPS or DUFFY ANTIGENs, makes them resistant . Fy=resistant. Fy^a or Fy^b = susceptible.
- P. vivax and P. ovale
5 True/False Questions
Definitive host of plasmodium is → mosquito
How do you get malaria? → Mosquito bite (sporozoite injection) or blood transfusion
John went backpacking in Asia and South America 8 years ago, and now he has malaria? How? → P. vivax can relapse after up to 8 years, fight it or treat it. Hypnozoite stage in liver is dormant stage.
Intermediate host of plasmodium is → human
What does P. falciparum do when it infects RBCs → asexual schizogony