intoxication and withdrawal

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Created by:

mattd05j  on March 16, 2010

Subjects:

behavioral science

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intoxication and withdrawal

alcohol intoxication
disinhibition, emotional lability, slurred speech, ataxia. SERUM GAMMA-GLUTAMYLTRANSFERASE (GGT). Treatment is naltrexone and disulfiram
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alcohol intoxication disinhibition, emotional lability, slurred speech, ataxia. SERUM GAMMA-GLUTAMYLTRANSFERASE (GGT). Treatment is naltrexone and disulfiram
alcohol withdrawal Tremor, tachycardia, hypertension, malaise, nausea, seizures, delerium tremens, tremulousness, agitation, HALLUCINATIONS (INCLUDING TACTILE). Tx for DT is benzodiazepines
opioid intoxication CNS depression, nausea and vomiting, constipation, pupillary constriction, seizures. Tx is naloxone and naltrexone
opioid withdrawal anxiety, insomnia, anorexia, sweating, dilated pupils, piloerection, fever, rhinorrhea, stomach cramps and diarrhea, yawning. Treatment is naloxone+ buprenorphine and methadone
Barbiturate intoxication Low safety margin, RESPIRATORY DEPRESSION
barbiturate withdrawal anxiety, seizures, delerium, life threatening cardiovascular collapse
benzodiazepine intoxication greater safety margin. Amnesia, ataxia, somnolence, minor respiratory depression. Additive effects with alcohol. Treatment is flumazenial
benzodiazepine withdrawal rebound anxiety, seizures, tremor, insomnia
amphetamine intoxication psychomotor agitation, impaired judgement, pupillary dilation, hypertension, tachycardia, euphoria, prolonged wakefulness and attention, cardiac arrhythmias, delusions, hallucinations, fever
amphetamine withdrawal post-use crash including depression, lethargy, headache, stomach cramps, hunger, hypersomnolence
cocaine intoxication euphoria, psychomotor agitation, impaired judgement, tachycardia, pupillary dilation, hypertension, HALLUCINATIONS (INCLUDING TACTILE), paranoid ideations, angina, sudden cardiac death. Treatment is benzodiazepines
cocaine withdrawal post-use crash including severe depression and suicidality, hypersomnolence, fatigue, malaise, severe psychological craving
caffeine intoxication restlessness, insomnia, increased diuresis, muscle twitching, cardiac arrhythmias
caffeine withdrawal headache, lethargy, depression, weight gain
nicotine intoxication restlessness, insomnia, anxiety, arrhythmias
nicotine withdrawal irritability, headache, weight gain, craving. Treatment is bupropion/varenicline
PCP intoxication BELLIGERENCE, impulsiveness, fever, psychomotor agitation, vertical and horizontal nystagmus, tachycardia, ataxia, homicidality, psychosis, delerium
PCP withdrawal Depression, anxiety, irritability, restlessness, anergia, disturbances of thought and sleep
LSD intoxication Marked anxiety or depression, delusions, visual hallucinations, FLASHBACKS, pupillary dilation
Marijuana intoxication Euphoria, anxiety, paranoid delusions, perception of slowed time, impaired judgment, social withdrawal, increased appetite, dry mouth, hallucinations
Marijuana withdrawal irritability, depression, insomnia, nausea. Most symptoms peak in 48 hours and last for 5-7 days. Can be detected in urine up to 1 month after last use

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