← Orgo Chem: Carboxylic Acid Derivatives Export Options Alphabetize Word-Def Delimiter Tab Comma Custom Def-Word Delimiter New Line Semicolon Custom Data Copy and paste the text below. It is read-only. Select All Acyl Halide R-C(=O)-X, suffix is -yl. Place the following in order of reactivity from highest to lowest. Esters. Anhydrides, amides, acyl halides Acyl Hallides > Anhydrides > Esters > Amides Convert acyl halide to ester React acyl halide with alcohol. Convert acyl halide to carboxylic acid React acyl halide with water (Hydrolysis) Convert acyl halide to amide React with amine Anhydride R-C(=O)-O-C(=O)-R What happens when anhydrides are exposed to water? They are converted in to two carboxylic acids. An acid + an alcohol = An Ester Suffix of ester -oate Transesterification Alcohols can act as nucleophiles and displace the alkoxy groups on esters. This process transforms one ester into another. Grignard reagents R-MgX. Will add the R group to the carbonyl carbon of another molecule, which can generate a ketone. This ketone is even more reactive than the carbonyl and will have grignard reagent attack again forming an alcohol compound with two R groups in addition. Claisen Condensation A carbon-carbon bond forming reaction that occurs between two esters or one ester and another carbonyl compound in the presence of a strong base to form Beta-Keto-Ester or a Beta-diketone. LAH and ester LAH is a very strong reducer and thus will reduce an ester to two primary alcohols.