5 Written questions
5 Matching questions
- terbutaline, orcipenaline
- a Antiplatelet. Monoclonal antibody that antagonises GIIb/a receptor on platelets, prevents binding of fibrinogen to platelets. Hospital use only.
- b short acting beta agonists (relievers for asthma).
- c Antihypertensive. Diuretic. Carbonic anhydrase inhibitor (acts at PCT) which inhibits H+ secretion and Na+ reabsorption.
- d DA agonist (directly stimulates D2 receptors in PD). SEs: nausea, hypotension, psychological effects, pleural effusions, retroperitoneal fibrosis, vasospasm. Used in combination with levodopa (reduces wearing off symptoms).
- e an imidazole antifungal (targets ergosterol synthesis via 14-aemethylase) - only used topically (vaginal/ skin)
5 Multiple choice questions
- Fibrinolytic. Plasminogen activator. Used only in acute thrombotic or embolic stroke.
- Antiplatelet. Blocks ADP receptor on platelets, therefore inhibits ADP-induced platelet aggregation. May cause severe bleeding.
- Benzimidazole - antihelmintic for intestinal nematodes e.g. threadworm, hookworm, whipworm, roundworm. Impairs microtubule synthesis.
Pooly absorbed from GIT, few SEs.
- aldoterone antagonist potassium-sparing diuretics (act on late DCT and collecting tubules). Used for CHF, and with thiazide or loop diuretics to produce diuresis without hypokalaemia.
- long acting beta agonists (symptom controllers for asthma). contraindicated with antihypertensives.
5 True/False questions
carbidopa, benserazide → DDCIs, used in combination with levodopa in PD.
ferrous sulphate → Oral iron therapy for iron deficiency anaemia. Continued for 2 - 3 months. SEs: nausea, abdominal cramps, constipation/ diarrhoea
griseofulvin → antifungal that targets nuclear division (inhibits microtubules)
cryoprecipitate → Obtained from blood donations. Contains concentrated vWF, given in severe vWD.
hydralazine → Antihypertensive (esp. in emergency) vasodilator (mainly arteriolar). Interferes with IP3 on Ca release from SR.