Ch. 16

Created by hallielane 

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D

The major categories of hypersensitivities that typically involve a B-cell immunoglobulin response is/are:
A. Type 1 only
B. Type 1 and Type 4
C. Type 4 only
D. Type 1, Type 2, Type 3
E. Type 1, Type 2, Type 3, and Type 4

A

Atopy and anaphylaxis are hypersensitivities in the category:
A. Type 1 only
B. Type 1 and Type 4
C. Type 4 only
D. Type 1, Type 2, Type 3
E. Type 1, Type 2, Type 3, and Type 4

C

All of the following are involved in Type 2 hypersensitivity except:
A. IgM
B. IgG
C. IgE
D. complement
E. foreign cells

B

The serum of a person with blood type A, Rh- will have which of the following?
A. anti A, anti Rh
B. anti B, anti Rh
C. anti A
D. anti B
E. anti A, anti B, anti Rh

B

A person with O type blood:
A. lacks all the alleles for ABO blood type
B. lacks A and B antigens
C. could not have the Rh factor
D. is called a universal recipient
E. all of the choices are correct

E

Transfusion of the wrong blood type can cause:
A. recipient antibody activating the complement cascade to
attack the RBCs
B. fever and anemia
C. systemic shock and kidney failure
D. massive hemolysis of the donor RBCs
E. all of the choices are correct

B

The potential for hemolytic disease of the newborn occurs when:
A. maternal Rh+ cells enter an Rh- fetus
B. fetal Rh+ cells enter an Rh- mother
C. maternal Rh- cells enter an Rh+ fetus
D. fetal Rh- cells enter an Rh+ mother
E. fetal Rh+ cells enter an Rh+ mother

C

Bee sting venom is considered to be which type of allergen?
A. ingestant
B. inhalant
C. injectant
D. contactant
E. none of the choices are correct

A

The initial encounter with an allergen is called the:
A. sensitizing dose
B. provocative dose
C. allergic dose
D. hypersensitivity dose
E. desensitizing dose

B

What will be the immediate action of an allergen when it enters that body for a second time?
A. degranulation
B. bonding of allergen to adjacent IgE binding sites on mast
cells and basophils
C. binding of IgE by the Fc region to mast cells and basophils
D. histamine acts on smooth muscle
E. prostaglandins cause vasodilation and increased vascular
permeability

D

Which of the following is not a possible symptom of Type I hypersensitivity?
A. rhinitis
B. rashes
C. sneezing
D. diarrhea
E. contact dermatitis

C

Any heightened or inappropriate immune response resulting in tissue damage is called a/an:
A. autoimmune disease
B. immunodeficiency
C. hypersensitivity
D. transfusion reaction
E. desensitization

A

Histamine causes all the following except:
A. increased sensitivity to pain
B. constriction of smooth muscle of bronchi and the intestine
C. relaxes vascular smooth muscle
D. wheal and flare reaction in skin
E. pruritis and headache

C

The chemical mediator that causes prolonged bronchospasm, vascular permeability, and mucus secretion of asthmatic patients is:
A. prostaglandin
B. histamine
C. leukotriene
D. serotonin
E. platelet-activating factor

B

Epinephrine:
A. is an antihistamine
B. reverses constriction of airways
C. causes desensitization
D. inhibits the activity of lymphocytes
E. all of the choices are correct

A

Allergic patients receiving small, controlled injections of specific allergens are undergoing:
A. desensitization
B. sensitization
C. tissue matching
D. degranulation
E. none of the choices are correct

E

Large quantities of antibodies that react to the second entry of antigen and lead to formation of antigen-antibody complexes occur in:
A. serum sickness
B. delayed hypersensitivity
C. anaphylaxis
D. hemolytic disease of the newborn
E. all of the choices are correct

E

Contact dermatitis involves:
A. a sensitizing and provocative dose
B. allergen entering the skin
C. T lymphocytes secrete inflammatory cytokines
D. itchy papules and blisters
E. all of the choices are correct

B

When grafted tissue such as bone marrow contains passenger lymphocytes what could result?
A. host rejection of graft
B. graft versus host disease
C. formation of autoantibodies
D. hypogammaglobulinemia
E. none of the choices are correct

C

The DiGeorge syndrome is the result of:
A. autoantibodies
B. delayed hypersensitivity
C. congenital absence or immaturity of the thymus gland
D. failure of B cell development and maturity
E. a genetic defect in the development of both T cells and B
cells

E

Severe combined immunodeficiencies (SCIDs) are due to:
A. autoantibodies
B. delayed hypersensitivity
C. congenital absence or immaturity of the thymus gland
D. failure of B cell development and maturity
E. a genetic defect in the development of both T cells and B
cells

A

A secondary acquired immunodeficiency is:
A. AIDS
B. adenosine deaminase (ADA) deficiency
C. DiGeorge syndrome
D. agammaglobulinemia
E. Type I diabetes

E

IgG is involved with which hypersensitivities
A. Anaphylaxis
B. Antibody mediated
C. Immune complex medieatd
D. Both Anaphylaxis and Antibody mediated
E. Both Antibody mediated and Immune complex medieatd

D

Allergic reactions to penicillins are considered a/an _____ hypersensitivity.
A. T-cell mediated
B. Antibody mediated
C. Immune complex mediated
D. Immediate
E. Both T-cell mediated and Antibody mediated

B

Tissue transplanted from one body site on a patient to a different body site on that patient is called an _____.
A. isograft
B. autograft
C. allograft
D. xenograft
E. none of the choices are correct

T

T/F
During graft rejection, cytotoxic T cells of the recipient recognize and respond to foreign class I MHC receptors on the grafted cells.

F

T/F
The most common immunoglobulin deficiency is an IgG deficiency.

T

T/F
A xenograft is graft tissue from a donor of one species transplanted to a recipient of another species.

T

T/F
Systemic anaphylaxis can quickly result in airway blockage, shock, and death.

F

T/F
A person who is Rh- will have anti Rh antibodies in their serum from early infancy.

Identical twins

Matching
Isograft

Rh incompatibility

Matching
Erythroblastosis fetalis

histamine

Matching
Mast cell

type I

Matching
Anaphylaxis

type IV hypersensitivity

Matching
Cell-mediated reactions

T cell defect

Matching
DiGeorge syndrome

both t and b cells defected

Matching
SCID

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