Patho Chapter 14

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The lining of the heart that forms a first line of defense against infection and inflammation is called the:
a. Exocardium
b. Myocardium
c. Endocardium
d. Pericardium

D. Pericardium.

A complete cardiac cycle includes:
a. One contraction and one relaxation phase
b. Two contractions and one relaxation phase
c. One contraction and two relaxation phases
d. Two contractions and two relaxation phases

A. One contraction and one relaxation phase.

The _______ of the heart contracts and relaxes.
a. Myocardium
b. Pericardium
c. Endocardium
d. Osteocardium

A. Myocardium.

Jennifer tells you that she had to have an ECG yesterday. She asks what this test measures. You tell her that it measures:
a. The myocardium thickness.
b. The resting phase of the myocardium.
c. The blood level in the heart.
d. The electrical activity of the heart.

D. The electrical activity of the heart.

Match the following ECG characteristics to the source:
_____ P wave
_____ PQ interval
_____ QRS
_____ T
_____ U

a. Depolarization of the AV node and bundle fibers.
b. Depolarization of the ventricles.
c. Repolarization of Purkinje fibers.
d. Depolarization of the atria via the SA node.
e. Repolarization of the ventricles.

D. Depolarization of the atria via the SA node.
A. Depolarization of the AV node and bundle fibers.
B. Depolarization of the ventricles.
E. Repolarization of the ventricles
C. Repolarization of Purkinje fibers.

The following is considered the pacemaker of the heart:
a. AV node
b. BA node
c. SA node
d. Purkinje fibers

C. SA node

Raymond recently had a myocardial infarction and tells you that his cardiologist told him that his cardiac output is decreased. Raymond asks you what his cardiac output is. You tell him that it measures the:
a. Heart's efficiency to pump optimal amounts of blood.
b. Number of heartbeats a minute.
c. Amount of blood that leaves the heart with each beat.
d. The mean arterial pressure.

A. Heart's efficiency to pump optimal amounts of blood.

The systolic blood pressure measures:
a. The difference between the diastolic and systolic pressure.
b. The amount of pressure that remains in the aorta during the resting phase of the cardiac cycle.
c. The amount of pressure exerted during contraction of the left ventricle.
d. The mean arterial pressure.

B. The amount of pressure that remains in the aorta during the resting phase of the cardiac cycle.

These are located throughout the heart and they sense pressure changes in the arteries:
a. Purkinje fibers
b. RA node
c. SA node
d. Baroreceptors

D. Baroreceptors.

The three major factors responsible for clot formation called Virchow triad include all of the following except:
a. Vessel wall damage
b. Excessive clotting
c. Alterations in blood flow
d. Hypocoagulation

D. Hypocoagulation.

Dale recently had a physical and was told by his physician's assistant that he had atherosclerosis. Dale is not sure what this means and asks you to explain it to him. You tell Dale that it is:
a. Irregularly distributed lipid deposits in the inner lining of arteries.
b. An autoimmune mechanism.
c. A place where the vessel branches.
d. An outpouching in the vessel wall.

A. Irregularly distributed lipid deposits in the inner lining of the arteries.

David has had a myocardial infarction and has large infarct in the right atrium. An infarct is a(n):
a. Area of necrosis due to an acute episode of insufficient blood supply.
b. Bifurcation of the artery.
c. Outpouching of the vessel wall.
d. Area of collateral circulation on the cardiac muscle.

A. Area of necrosis due to an acute episode of insufficient blood supply.

Blood movement across the chambers of the heart is referred to as:
a. Shunting
b. Regurgitation
c. Stenosis
d. Dysrhythmia

A. Shunting.

Elmer has a valve that is unable to close properly and allows reflux of blood. This is called:
a. Shunting
b. Regurgitation
c. Stenosis
d. Dysrhythmia

B. Regurgitation.

Carie has an allergy to penicillin. Her provider mistakenly prescribed this medication for her infection. Shortly after taking the medication, Carie experienced a massive immune hypersensitivity response and moved into a state of shock. This type of shock is called:
a. Hypovolemic shock
b. Septic shock
c. Neurogenic shock
d. Anaphylactic shock

D. Anaphylactic shock.

anaphylactic shock

a condition of impaired tissue perfusion from shock because of a massive immune (type 1 or IgE-mediated) hypersensitivity response


local out pouching caused by weakness in the vessel wall

angina pectoris

chest pain or pressure that is intermittent and associated with myocardial ischemia, a reduction in blood flow to the coronary arteries caused by atherosclerosis often accompanied by vasospasm

atrioventricular node (AV)

`connects the conduction of impulses between the atria and ventricles


located throughout the blood vessels and the heart; sense pressure changes in the arteries and alert the cardiac control center in the brainstem


regions wherein a vessel branches

blood pressure

the pressure or tension of the blood within the systemic arteries

cardiac cycle

refers to one contraction and one relaxation phase of the heart

cardiac dysrhythmias

a category of problems with maintaining an efficient heart rhythm, such as impairments of the sinoatrial (SA) node, atrioventricular (AV) node, cardiac cells that join the SA and AV nodes, or conduction systems int he atria or ventricles

cardiac output (CO)

the volume of blood pumped from the ventricles in 1 minute

congestive heart failure

occurs when the left ventricle of the heart is ineffective and blood backs up into the pulmonary vein and subsequently into the lung tissues; results in pulmonary edema; also called left heart failure

cor pulmonale

an alteration in the structure and function of the right ventricle caused by a primary disorder of the respiratory system


the relaxation of the heart that allows blood to fill the ventricles

diastolic blood pressure

the amount of pressure that remains in the aorta during the resting phase of the cardiac cycle

diastolic failure

failure that occurs with stiffness of the ventricle and loss of relaxation ability, which impairs the heart's ability to optimally fill with blood between cardiac contractions

disseminated intravascular coagulation (DIC)

a condition of uncontrolled activation of clotting factors resulting in widespread thrombi formation followed by depletion of coagulation factors and platelets; leads to massive hemorrhage


bruises from superficial bleeding into the skin


any plug of material, such as thrombi, air, neoplasms, microorganisms, or amniotic fluid, that travels in the circulation and can obstruct the lumen of the vessel


the inner lining of the heart that forms a continuous layer of endothelium that joins the arteries and veins to the heart, forming a closed circulatory system


a problem of the heart chamber vibrating instead of effectively pumping


a dissolution of blood clots

heart block

the obstruction of cardiac conduction, often at the atrioventricular node,leading to heart dysrhythmias

heart failure

reflects an inadequacy of heart pumping so that the heart fails to maintain the circulation of blood

heart rate

the number of heartbeats that occur in 1 minute


large accumulations of blood in the tissue


the loss of blood through the vessel wall

Homans sign

a test of foot dorsiflexion, which, in the presence of deep vein thrombosis, causes pain in the back of the lower leg


an elevation in blood pressure commonly defined by a systolic pressure above 140mmHg or a diastolic pressure above 90mmHg


a condition of reduced blood pressure

hypovolemic shock

the result of inadequate blood/plasma volume


an area of necrosis resulting from a sudden insufficiency of arterial or venous blood supply


the process of obstructing a blood vessel

isolated systolic hypertension

an elevation in systolic blood pressure without an elevation in the diastolic blood pressure

mean arterial pressure

an adequate measure of systemic tissue perfusion; is calculated as one third of the pulse pressure plus diastolic pressure

myocardial infarction

the total occlusion of one or more coronary arteries resulting in ischemia and death of myocardial tissue


the thick muscular layer of the heart

neurogenic shock

a result of brain or spinal cord injury in which altered neuronal transmission leads to a loss of tension in the blood vessels, allowing unregulated vasodilation, decreased peripheral vascular resistance, and reduced blood pressure; oxygenated blood is not: shunted to vital organs, and perfusion to vital organs is reduced.


the process of forcing blood to other fluid to flow through a vessel and into the vascular bed of a tissue for the purposes of providing oxygen and other nutrients.


the outer covering of the heart,which holds the heart in place in the chest cavity, contains receptors that assist with the regulation of blood pressure and heart rate, and forms a first line of defense against infection and inflammation


pinpoint hemorrhages of the skin or mucous membranes

pulse pressure

the difference between the systolic and diastolic blood pressure


the presence of diffuse hemorrhages of the skin or mucous membranes


the problem of incompetence of the valve; the valve is unable to properly close, allowing reflux of the blood

septic shock

a condition of altered perfusion by shock as the result of overwhelming systemic infection, often with gram-negative
bacteria (the endotoxin component) leading to inadequate perfusion of vital organs


the movement of blood across the atria or ventricles of the heart

sinoatrial (SA) node

the pacemaker of the heart, which generates a rhythmic impulse in the atria


a problem in which narrowing of the valve occurs, aking it unable to open adequately


any clinical event, such as shock, cerebral hemorrhage, ischemia, or infarction, that leads to the impairment of cerebral circulation

stroke volume

the amount of blood pumped out of one ventricle of the heart in a single beat


a heart contraction that forcefully moves blood out of the ventricles

systolic blood pressure

the amount of pressure exerted during contraction of the left ventricle and ejection of blood into the aorta

systolic failure

heart failure caused by a loss of contractile ability of the heart


a condition of excess platelets in the blood


a situation in which a thrombus breaks off within a vessel and travels to another location in the body


a formation of a blood clot

transient ischemic attack (TIA)

a brief period of inadequate cerebral perfusion causing a sudden focal loss of neurologic function; full recovery of function usually occurs within 24 hours

ventilation-perfusion ratio

the relationship between inspired oxygen and the pulmonary circulation, which is responsible for transporting the oxygen to the heart to be pumped to the rest of the body. this is expressed as a ratio and is typically 0.8-0.9, where the rate of ventilation is usually less than the rate of perfusion

venous stasis

stagnation of blood in the veins with reduced venous return

Virchow triad

three major factors are responsible for thrombus formation; vessel wall damage, excessive clotting, and alterations in blood flow, such as turbulence or sluggish blood movement.

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