physiology progress test one
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10 terms
Terms | Definitions |
|---|---|
 what does creb stand for? | cAMP Response Binding Element |
| what are the four main enzyme-linked receptors? | Guanylate cyclase receptors / threonine/serine receptors / tyrosine kinase receptors / tyrosine kinase associate receptors. |
| What does the guanylate cyclase receptor respond to? | atrial natriuretic peptide (anp...activates the membrane receptor). and NO (activates the soluble receptor). |
| what does tyrosine kinase receptors respond to? | Nerve growth factor, insulin |
| What are the two inputs which may start the MAPK pathway? | tyrosine kinase and PKC |
| Describe the MAPK pathway | growth factor binds, activates tyrosine kinase receptor, activates, ras and raf (small g protein) which start MAP kinase pathway...downstream activation by phosphorylation. |
| Calcium and calmodulin | Make NO synethesis increase (NOS is ca2+ dependent). |
| acetyl choline | this is the agonist the activates eNOS in and endothelial cell. NO goes on to activate guanylate cyclase which turns GTP into cGMP...vasodilation role. |
| paracrine | NO as a neurotransmitter is this |
| Role NO has on memory is...? | Helps long term potentiation. NO travels by diffusion. |
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