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5 Written questions

5 Matching questions

  1. pharmacokinetics
  2. pharmacodynamics
  3. C min
  4. Good whole food vitamin
  5. cons of oral/enteral administration
  1. a describes action of drugs wihtin body and absorption, [How drugs move in body and how quickly] distrib, metabolism and elimination of drugs in addition to the rate or kinetics at which drug's actions begin and their duration. "ADD ME" (sp?) scheme
  2. b looks at how drugs act in the body and deals with [At the site of action, what the drug does] mechanisms of action in addition to the actions of different drug concentrations or doses
  3. c minimum trough concentration
  4. d reduced drug absorption, emesis due to gastrointestinal irritation, destruction of some of drug thru enzymatic degradation and gastric acid, inconsisten absorption, and patient compliance issues
  5. e New process

5 Multiple choice questions

  1. the prcoess thru which the drug leaves the bloods tream and enters interstitium (absorption is about intestines, distrib is about bloodstream). 4 aspects: blood flow, capillary permeability, drug structure, degree of binding to proteins
  2. brain, liver, kidneys have excellent blood flow, skeletal muscles and skin less, adipose tissues even less.
  3. most drugs reversibly bind to plasma proteins. drugs bound to albumin is going to be inactive. albumin is the most common protein in the plasma, albumin keeps blood within the blood vessels. As plasma concentration of the drug increases, more binding occurs.
  4. time for drug concentration to fall by half
  5. inhalation, intranasal, topical, transdermal (nicotine patches)

5 True/False questions

  1. sublingual and rectal administrationreduced drug absorption, emesis due to gastrointestinal irritation, destruction of some of drug thru enzymatic degradation and gastric acid, inconsisten absorption, and patient compliance issues

          

  2. charge of drugdetermine how readily crosses membrane. uncharged chemicals more easily pass membranes. weak acids and bases can be charged or uncharged, but each drug's charge changes based on interaction with body's pH

          

  3. ADME schemeabsorption, distribution, metabolism and elimination.

          

  4. very hydrophobic drugsdetermine how readily crosses membrane. uncharged chemicals more easily pass membranes. weak acids and bases can be charged or uncharged, but each drug's charge changes based on interaction with body's pH

          

  5. passive diffusionphysiochemical makeup helps determine how easy or difficult drug passes thru membranes (concentration gradient, how lipophilic and surface area of cell)

          

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