Respiratory System Homework - Pathophysiology

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Patho Respiratory Homework

What happens in the lungs when the diaphragm relaxes?

Air is forced out of the lungs.

The respiratory mucosa is continuous through the: upper and lower respiratory tracts, nasal cavities, and the sinuses, nasopharynx and oropharynx, middle ear cavity and auditory tube

E, all of the above

Which of the following activities does NOT require muscle contractions and energy?

quiet expiration

The maximum volume of air a person can exhale after a maximum inspiration is termed the:

vital capacity

Which of the following applies to the blood in the pulmonary artery?

PO2 is low.

Which of the following causes bronchodilation?

epinephrine

The central chemoreceptors are normally most sensitive to:

elevated carbon dioxide level

Oxygen diffuses from the alveoli to the blood because:

PO2 is lower in the blood.

Carbon dioxide is primarily transported in the blood:

as bicarbonate ion

What would hypercapnia cause?

respiratory acidosis

Which of the following would result from hyperventilation?

respiratory alkalosis

Which of the following values is always decreased with respiratory alkalosis (compensated or decompensated)?

PaCO2

What would be the most effective compensation for respiratory acidosis?

the kidneys producing more bicarbonate ions

What is the acid-base status of a patient with the following values for arterial blood gases? serum bicarbonate 36.5 mmol/L (normal range: 22-28), PCO2 75 mm Hg (normal range: 35-45), serum pH 7.0

decompensated respiratory acidosis

What does carbaminohemoglobin refer to?

carbon dioxide attached to an amino group on the hemoglobin molecule

How is oxygen toxicity manifested?

increased pulmonary compliance with diffuse atelectasis

How is respiratory failure defined?

PaO2 less than 50 mm Hg or PaCO2 greater than 50 mm Hg

What does the term hemoptysis refer to?

bright red streaks of blood in frothy sputum

Orthopnea is:

difficulty breathing in a recumbent position

Choose the correct information applying to laryngotracheobronchitis:

viral infection in child, 3 months to 3 years

Signs and symptoms of acute sinusitis usually include:

severe localized pain and tenderness in the face

What are early signs and symptoms of infectious rhinitis?

serous nasal discharge, congestion, and sneezing

Why does the influenza virus cause recurrent infection in individuals?

Viral mutation reduces immunity from prior infections.

What are typical signs and symptoms of epiglottitis?

sudden fever, sore throat, and drooling saliva

What is the most common cause of viral pneumonia?

influenza virus

Which of the following describes lobar pneumonia?

sudden onset of fever and chills, with rales and rusty sputum

How does severe hypoxia develop with pneumonia?

oxygen diffusion is impaired by the congestion

Rust-colored sputum in a patient with pneumonia usually indicates:

Streptococcus pneumoniae is the infecting agent

What is the cause of Legionnaires' disease?

a gram-negative bacterium

Select the statement related to tuberculosis:

The microbe is an acid-fast bacillus, resistant to many disinfectants.

How is primary tuberculosis identified?

caseation necrosis and formation of a tubercle in the lungs

When does active (secondary) infection by M. tuberculosis with tissue destruction occur?

Host resistance is decreased for any reason.

Which of the following statements does NOT apply to M. tuberculosis?

Microbes can survive for a long time inside tubercles.

Which of the following confirms the presence of active (reinfection) tuberculosis?

identification of acid-fast bacilli in a sputum sample

Which of the following is a major factor contributing to the current increase in cases of tuberculosis?

the increase in immunodeficient individuals

Histoplasmosis is caused by a:

fungus

Cystic fibrosis is transmitted as a/an:

autosomal recessive gene

The basic pathophysiology of cystic fibrosis is considered to be:

an abnormality of the exocrine glands

Growth and development of a child with cystic fibrosis may be delayed because of:

mucus plugs obstructing the flow of pancreatic enzymes

Persistent thick mucus in the bronchioles of a child with cystic fibrosis may cause: air trapping, atelectasis, repeated infections, irreversible damage to lung tissue.

D, All of the above

What is a common indicator of cystic fibrosis in the newborn?

failure to excrete meconium

What is an early sign of bronchogenic carcinoma?

chronic cough

Cigarette smoking predisposes to malignant neoplasms because smoking:

causes metaplasia and dysplasia in the epithelium

Why does hypercalcemia occur with bronchogenic carcinoma?

secretion of parathyroid or like hormone by the tumor

What is a sign indicating total obstruction of the airway by aspirated material?

rapid loss of consciousness

Which of the following predisposes to postoperative aspiration?

depression of the cough and swallow reflexes by drugs

What is the pathophysiology of an acute attack of extrinsic asthma?

type 1 hypersensitivity reaction

During an acute asthma attack, how does respiratory obstruction occur?

edema of the mucosa, increased secretion of thick, tenacious mucus. C, 2 and 3.

What cause the expanded A-P thoracic diameter (barrel chest) in patients with emphysema?

air trapping and hyperinflation

Which of the following is typical of progressive emphysema?

Residual lung volume increases.

Destruction of alveolar walls and septae is a typical change in:

emphysema

When patients with chronic hypercapnia are administered oxygen:

blood levels of oxygen should remain slightly below normal

Which statement does NOT apply to emphysema?

The ventilation/perfusion ratio remains constant.

What is the cause of chronic bronchitis?

chronic irritation, inflammation, and recurrent infection of the larger airways

Which of the following are typical of chronic bronchitis?

fibrosis of the bronchial wall

What are typical pathological changes with bronchiectasis?

airway obstructions are weak, dilated bronchial walls

Which of the following are significant signs of bronchiectasis?

chronic cough producing large quantities of purulent sputum

Why does cor pulmonale develop with chronic pulmonary disease?

Pulmonary fibrosis and vasoconstriction increase vascular resistance.

What are common signs of cor pulmonale?

hepatomegaly and edema in the legs

What is caused by frequent inhalation of irritating particles such as silica?

fibrosis and loss of compliance

Pulmonary edema causes severe hypoxia because of:

increasing difficulty expanding the lungs

Which of the following is NOT a cause of pulmonary edema?

hyperproteinemia and increasing osmotic pressure of the blood

Which of the following is a common source of a pulmonary embolus?

thrombus forming in the femoral veins

What is a large-sized pulmonary embolus likely to cause?

ral effusion and atelectasis

Which manifestation(s) of atelectasis is/are associated with airway obstruction?

decreased breath sounds on the affected side

How does total obstruction of a major bronchus lead to atelectasis?

Air is absorbed from the alveoli distal to the obstruction.

How does a large pleural effusion cause atelectasis?

The cohesion between the pleural membranes is disrupted.

When does flail chest occur?

Several ribs are fractured at two sites.

With a flail chest injury, events during inspiration include:

the mediastinum shifts toward the unaffected side

How is cardiac output reduced with a flail chest injury?

Venous return is impaired.

Which of the following is a manifestation of a simple closed pneumothorax?

asymmetrical chest movements

Which of the following is an effect of a large open pneumothorax (sucking wound)?

mediastinal flutter

With a tension pneumothorax, which factors contribute to severe hypoxia?

continually increasing pressure on the unaffected lung

Which of the following statements describe the pathophysiology of adult respiratory distress syndrome?

damage leading to increased permeability of the alveolar walls, excessive fluid and protein interstitially and in the alveoli. B, 1 and 3

Infant respiratory distress syndrome results from:

insufficient surfactant production

Obstruction in the upper airway is indicated by:

stridor

Which of the following does NOT apply to carbon dioxide?

It is replaced on hemoglobin by oxygen in the lungs.

Whenever PO2 levels decrease below normal, then PCO2 levels:

may or may not change

Laryngotracheobronchitis is typically manifested by:

hoarse voice and barking cough

Lobar pneumonia is usually caused by:

Streptococcus pneumonia

Severe acute respiratory syndrome (SARS) is caused by a/an:

Coronavirus

SARS typically begins as a flulike syndrome followed after a few days by:

interstitial lung congestion, dyspnea, and dry cough

In addition to effects on the lungs and pancreas, cystic fibrosis causes:

high sodium chloride content in saliva and sweat

Which of the following is a significant early sign of bronchogenic carcinoma in a smoker?

hemoptysis and weight loss

Which of the following is likely to cause pneumothorax or hemothorax in a patient with bronchogenic carcinoma?

The tumor causes inflammation and erosion of the pleural membranes.

Which of the following would confirm a diagnosis of primary tuberculosis?

sputum containing TB bacilli

Which of the following drugs is usually prescribed for prophylaxis in persons in close contact with a patient with active tuberculosis?

Isoniazid

Which of the following statements is FALSE?

Active TB must be treated in hospital for many months.

Choose the correct reason for severe hypoxia occurring with pulmonary edema:

Diffusion of oxygen into the pulmonary capillaries is impaired.

Which of the following drugs in an inhaler would likely be carried by individuals to provide immediate control of acute asthma attacks?

a beta-2-adrenergic agent

Which of the following values for arterial blood gases would be expected in a patient with advanced emphysema?

increased PCO2, increased bicarbonate ion, serum pH 7.35

Which factors contribute to postoperative atelectasis?

drug-related respiratory depression, abdominal distention and pain. B, 2 and 3

Pleurisy associated with lobar pneumonia is manifested by:

cyclic chest pain and friction rub

All of the following are expected with infant respiratory distress syndrome EXCEPT:

respiratory alkalosis

Which factor usually causes metabolic acidosis to develop in association with hypoxia?

anaerobic metabolism

Mediastinal flutter associated with chest injury is likely to:

decrease venous return to the heart

Which of the following individuals is NOT considered to be at high risk for developing active tuberculosis?

persons who experience acute asthma attacks

Which of the following distinguishes influenza from infectious rhinitis?

Influenza has a sudden onset with fever, marked muscle aching, and severe malaise.

The use of a continuous positive airway pump in the treatment of sleep apnea will:

prevent collapse of pharyngeal tissues

Hemoptysis is a significant sign of:

pulmonary edema

Which of the following applies to anthrax infection?

when it is inhaled it causes flulike symptoms followed by acute respiratory distress

The mutated gene for cystic fibrosis is located on the:

seventh chromosome

Aspiration pneumonia is usually caused by aspiration of:

liquids such as oils or milk

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