← Pharma Chap5 Export Options Alphabetize Word-Def Delimiter Tab Comma Custom Def-Word Delimiter New Line Semicolon Custom Data Copy and paste the text below. It is read-only. Select All Angioedema Large circumscribed area of subcutaneous edema of sudden onset frequently caused by an allergic reaction. Anhedonia Inability to feel pleasure or happiness from activities that would normally provide such feelings. Ataxia Incoordination of voluntary muscles resulting in jerky movements that may affect the limbs, head, or trunk. Autoreceptors A receptor located on a neuron that binds a neurotransmitter from the same neuron which then regulates that neuron. Blood dyscrasia Abnormal condition of the blood. Catabolism Biological processes which primarily break down large storage and other chemicals, often releasing energy in the process. Catecholamines Sympathomimetic neurotransmitter family that includes epinephrine, norepinephrine, and dopamine. Cor pulmonale Damage to the heart and lungs due to a pathology in the pulmonary circulation. Dependence The psychological and physical need for a substance. Dyskinesia Impairment or inability to execute voluntary movements. Dysphoria A disorder of mood characterized by depression and anguish. Excitatory postsynaptic potential (EPSP) An increase of voltage that increases the likelihood of an action potential and a nerve impulse. Extrapyramidal symptoms Exhibiting movement disorders, especially postural and locomotor, resembling Parkinson's disease. Fetal hydantoin syndrome A rare disorder caused by fetal exposure to phenytoin. Symptoms include skull and facial abnormalities, underdevelopment of the nails and overall growth, mild developmental delays, and possibly a cleft lip and palate. Hepatotoxic Toxic to the liver. Hyperpolarization The state where a neuron's membrane is more electrically negative than normal and therefore it is much more difficult to initiate an action potential. Glycosuria An abnormal increase of glucose in the urine. Hyperplasia An increase in the number of cells of a given body part. Hypomania A condition similar to mania but less severe in its symptoms. Inhibitory postsynaptic potential (IPSP) A decrease of voltage that decreases the likelihood of an action potential and a nerve impulse. Ischemia Decreased blood flow to an organ or body part, often accompanied by pain and dysfunction. Megaloblastic anemia A blood disorder characterized by the production and proliferation of immature, large, and dysfunctional red blood cells, usually associated with pernicious anemia and folic acid deficiency. Micrographia Very small writing Monoamine oxidase (MAO) An enzyme that metabolizes norepinephrine and other catecholamines. Myoglobinemia Abnormal presence of myoglobin in the blood indicating muscle breakdown. Nystagmus Involuntary, rhythmic, movements of the eyes, may be horizontal, vertical, rotary, or mixed. Orthostatic hypotension A period of reduced blood pressure due to standing rapidly from a seated or lying position, usually causes lightheadedness. Psychosis A severe emotional and behavioral disorder that includes symptoms of gross distortion of a person's mental capacity, ability to recognize reality, inability to relate to others, or perform ADLs. Status epilepticus A condition of a sustained epileptic seizure that can be life threatening. Striatum (also referred to as corpus striatum or neostriatum): The part of the basal ganglia of the brain that includes the caudate nucleus and putamen. Its function is to plan and modulate movement and in some higher cognitive functions. Lack of dopamine prevents the proper modulating function in Parkinson's Disease. Synapse A junction between 2 nerves or a nerve and an effector organ. Synaptic cleft /space The space between the two neurons of a synapse; the space into which the neurotransmitters are released. Tardive dyskinesia A motor disorder that includes involuntary movements such as lateral jaw movements and "fly-catching"movements of the tongue Teratogen A substance that causes congenital defects in fetuses. Tolerance The need for increasing doses of a substance in order to maintain the same effect or to avoid negative symptoms. Urticaria Skin condition consisting of wheals, usually the result of hypersensitivity; commonly called hives. Withdrawal The psychological and/or physical syndrome caused by abrupt cessation of the use of a drug in a habituated individual.