CC 4 stroke
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22 terms
Terms | Definitions |
|---|---|
 50 ml/100g/min | normal rate of CBF |
| 25ml/100g/min | CBF decreases to this rate and neurons stop firing but are still viable: ischemic penumbra |
| 10ml/100g/min | CBF decreases to this rate and brain cells are irreversibly dead r/t lactic acidosis and cytotoxic edema |
| causes of ischemic stroke | large artery artherosclerosis, cardioembolic events, small artery occlusive disease |
| large artery artherosclerosis | caused by cholesterol plaque, thrombus on plaque or embolis |
| risk factors for large artery artherosclerosis (and also for stroke) | HTN, Diabetes, smoking and possibly high cholesterol |
| cardioembolic stroke | caused by A fib, rheumatic heart disease, AMI, endocarditis, mitral valve stenosis and prosthetic heart valves |
| mechanism of action of cardioembolic stroke | clot formation due to low flow of blood from the heart |
| cardiac abnormality is the source of the emboli causing stroke in the first place | why important to treat underlying cardiac problem as well as neuro problem when someone has cardioembolic stroke? |
| lacunar stroke | HTN, Diabetes, small vessel occlusive disease cause this type of stroke where fat coats cerebral arteries in brain and thickens walls causing stroke |
| places in brain lacunar stroke most often occurs | basil ganglia, sub cortical white matter, thalamus, cerebellum and brainstem |
| 10 -12 x's more often | Lucunar strokes occur how much more often than other types of stroke? |
| vascular dementia | one of the cognitive deficits caused by lucunar stroke |
| pure motor, pure sensory or both | patients can present with which features when they have a lucunar stroke? |
| primary causes of hemorrhagic stroke | primary intraparenchymal hemorrhage, ruptured cerebral aneurysm, AV malformation |
| secondary causes of hemorrhagic stroke | over anticoagulation (heparin, warfarin or rtPa), vasopressors, cocaine abuse, liver or renal failure, thrombcytopenia |
| bleeding into brain substance from uncontrolled HTN | cause of intraparenchymal hemorrage |
| 10% | percentage of hemorrhagic strokes caused by intraparenchymal hemorrhage |
| location of bleeding, compression and herniation | what does the severity of stroke from intraparenchymal hemorrhage depend on? |
| risk of rupture and hemorrhage into sub arachnoid space | what does AV malformation increase the risk of? |
| impaired perfusion | AV malformation impairs what? |
| complications of AV malformation | ischemia, scarring of brain tissue, abnormal tissue development, compression, hemorrhage and hydrocephalus |
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