Renal Pathology
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25 terms
Terms | Definitions |
|---|---|
 most common nephrotic syndrome in children | minimal change disease |
| IF: granular pattern of immune complex depostion LM: diffuse capillary thickening | membranous glomerulonephritis |
| IF: granular pattern of immune complex depostion LM: hypercellular glomeruli | acute post strep GN |
| IF: linear pattern of immune complex deposition | Goodpastures (rapidly prgressive/crescentic GN) |
| IF: deposition of IgG, IgM, IgA, and C3 in mesangium | Berger's |
| Kimmelstiel-Wilson lesions (nodular glomerulosclerosis) | diabetic GN |
| most common nephrotic syndrome in adults | membranous GN |
| EM: loss of epithelial foot processes | minimal change disease |
| nephrotic syndrome a/w Hep B | membranoproliferative GN, Type 1 And membranous GN (according to Dr. Rizk) |
| nephrotic syndrome a/w HIV | focal segmental GN |
| anti-GBM antibodies, hematuria, hemoptysis | Goodpasture's |
| EM: subendothelial humps and tram track appearance | membranoproliferative GN |
| nephritis, deafness, cataracts | Alport's |
| LM: cresent formation in the glomeruli | rapidly progressive GN |
| LM: segmental sclerosis and hyalinosis | focal segmental GN |
| purpura on back of arms and legs, abdominal pain, IgA nepropathy | Henloch Schoenlein |
| LM: Wire loop appearance | diffuse proliferative GN |
| apple green birefringence with Congo red stain under polarized light | amyloidosis |
| EM: spiking of the GBM ue to electron dense subepithelial deposits | membranous |
| RBC casts | glomerulonephritis, ischemia, malignant hypertension |
| WBC cast | tubulointerstitial inflammation, acute pyelonephritis, transplant rejection |
| bacterial cast | acute pyelonephritis |
| epithelial cell cast | renal tubular damage |
| waxy cast | renal failure |
| granular cast | acute tubular necrosis |
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