Skeletal muscle system

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Created by:

nycnazifa  on June 26, 2010

Subjects:

BIO 203

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Skeletal muscle system

Fascicle
a discrete bundle of muscle cells
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Definitions

Fascicle a discrete bundle of muscle cells
perimysium Connective tissue surrounding a fascicle
Epimysium Connective tissue layer surrounding an individual muscle
Sarcolemma The specific name of the cell membrane of a muscle fiber
Sarcoplasmic reticulum specialized endoplasmic reticulum of muscle cells that stores Ca+
Terminal Cisternae Sac like structures that surround both side of a T-Tubule serves as reserivors for calcium ions
T-tubule an invagination of the sarcolemma that projects deep into the muscle cell's interior
Triad a Three unit group of one t-tubule lying adjacent between two Terminal Cisternae
Myofibril one of many contractile filaments that make up a striated muscle fiber
Myofilaments Contractile proteins that slide pass one another
a bands dark bands of the muscle made of myosin
I band lights bands gets smaller when muscle contacts
Z line discets the Light bands (I bands)
H zone at the M-line that gets shorter as the muscle contracts like the I-band
neuromuscular junction specialized synaptic junction btw a motor neuron and a skeletal muscle fiber
graded and depolarized The motor end-plate potential generated by the synaptic release of acetylcholine (ACh) is always
suprathreshold the amplituded of the end plate potential is always
depolarizes when a motor neuron _______ ACh is released and the muscle fiber attached to it contracts
True During muscle contraction, cytosolic Ca2+is high, allowing actin and myosin to interact. Ca2+ binding induces a conformational change in the thin filament and its regulatory proteins exposing the myosin-binding site on actin.
true During muscle relaxation, cytosolic Ca2+is low and tropomyosin is covering the myosin-binding site on acting preventing cross-bridge formation. The binding site of Ca2+ is on troponin.
true In skeletal muscle, an action potential traveling down a t-tubule will result in the opening of an intracellular ion channel followed by the conformational change of the thin filament.
nebulin protein anchored at Z-line and runs length of actin filament
titin anchors the actin molecule and is the largest known protein in humans

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