ch 15, objective 2
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7 terms
Terms | Definitions |
|---|---|
 lymphokines | cytokines primarily produced by lymphocytes.released in chronic lymphocytic inflammatory lesions, contribute to chronic pain. |
| endorphins | an endogenous opioid that inhibit transmission of pain impulses in the spinal cord and brain. endogenous opioids inhibit the release of excitatory neurotransmitters like substance P in the dorsal horn. INHIBITORY TRANSMITTER |
| prostaglandins | released as a result of tissue injury, promote the spread of pain locally and contribute to vasodialation, increased vascular permeability and degranulation of even more cytokines INFLAMMATORY MEDIATOR |
| bradykinins | a protein produced that acts to stimulate vasodilation and pain receptor activation. Released during tissue injury and promote pain INFLAMMATORY MEDIATOR |
| histamine | a hormone that is produced by mast cells and functions to dialate capillaries so that they are more permeable. Released during tissue injury and promote pain |
| cytokine | molecule produced by cells that mediate interactions between cells during the inflamatory response |
| Neurotransmitters | can be inflamatory, pain excitatory, pain inhibitory, modulators of pain. |
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