cytokines primarily produced by lymphocytes.released in chronic lymphocytic inflammatory lesions, contribute to chronic pain.
an endogenous opioid that inhibit transmission of pain impulses in the spinal cord and brain. endogenous opioids inhibit the release of excitatory neurotransmitters like substance P in the dorsal horn. INHIBITORY TRANSMITTER
released as a result of tissue injury, promote the spread of pain locally and contribute to vasodialation, increased vascular permeability and degranulation of even more cytokines INFLAMMATORY MEDIATOR
a protein produced that acts to stimulate vasodilation and pain receptor activation. Released during tissue injury and promote pain INFLAMMATORY MEDIATOR
a hormone that is produced by mast cells and functions to dialate capillaries so that they are more permeable. Released during tissue injury and promote pain
molecule produced by cells that mediate interactions between cells during the inflamatory response
can be inflamatory, pain excitatory, pain inhibitory, modulators of pain.