Prevents the sythesis of peptidoglycan components by competatively inhibiting D-alanine ligase and alanine racemase. A D-ala sidechain mimetic.
Inhibits the transfer of peptidoglycan components across the cell membrane by preventing dephosphorylation of C55 isoprenyl pyrophosphate
Prevents the incorporation of N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) peptide subunits into the peptidoglycan matrix
Prevents cross linking between N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) peptide subunits in the peptidoglycan matrix. Ex: penicillins, cephalosporins, monobactams, carbapenems