Alanine, Ala, A
Arginine, Arg, R Side chain amino pKa = 12.5 basic.
Asparagine, Asn, N
Aspartic acid, Asp, D Carboxy side chain pKa = 3.9
Cysteine, Cys, C Side chain SH pKa = 8.3 slightly basic.
Glutamic acid, Glu, E Carboxy side chain pKa = 4.3
Glutamine, Gln, Q
Glycine, Gly, G
Histidine, His, H imidazole pKa = 6.0 slightly acidic
isoleucine, Ile, I
Methionine, Met, M
Phenylalanine, Phe, F
leucine, leu, L
lysine, Lys, K Amino side chain pKa = 10.5 basic
Proline, Pro, P
Serine, Ser, S
Threonine, Thr, T
Tryptophan, Trp, W
Tyrosine, Tyr, Y
Valine, Val, V
What are the pKa's usually of the carboxy and amino termini for all amino acids?
carboxy group usually has pKa of 2. amino terminus has pKa around 9.
***What amino acids have side chains with a pKa and what are the pKa's? Why?
1. Acidic things - Aspartic Acid, D, pKa 3.9 and Glutamic Acid, E, pKa 4.3
2. Basic things - Arginine, R, pKa 12.5 and Lysine, K, pKa 10.5
3. Other exceptions - Histidine, H, 6.0 and Cysteine, C, pKa is 8.3
Give me the nonpolar, polar, and charged amino acids. List them by name!
Nonpolar: glycine, alanine, valine, leucine, isoleucine, methionine, tryptophan, phenylalanine, proline
Polar: Serine, threonine, cysteine, tyrosine, asparagine, glutamine
Charged acidic (OH under pKa, O- above pKa) : Aspartic acid, glutamic acid
Charged basic (NH3+ under pKa, NH2 above pKa) - Lysine, arginine, histidine
Name the strange letter amino acids and their one letter symbols
Tryptophan=W, Phenylalanine=F, Tyrosine=Y, Asparagine = N, Glutamine = Q, Aspartic acid = D, Glutamic acid = E, Lysine = K, Arginine = R