5 Written Questions

1. small shiny bump (enlarges into a central depression, beaded "pearly" edge)
2. deviation of the great toe medially
3. defective mineralization of bone in children (Vit D deficiency)
4. inflammation of soft tissue of 1st MTP joint followed by bone deposition
5. painful overstretching of a tendon or muscle without serious tissue damage

5 Matching Questions

1. Marfan's Syndrome
2. Dislocation
3. Rash
4. Tay-Sachs disease
5. Sprain

1. a lysosomal storage disease; glycolipids are endocytosed & accumulate in neurons of brain
2. b displacement of a bone from its normal position at a joint
3. c abnormal expression of the fibrillin 1 gene
4. d torn ligament or tendon
5. e inflammatory skin condition or a dermatitis

5 Multiple Choice Questions

1. a red rashlike area (nose & cheeks) marked by fine networks of dilatd blood vessels
   1. Acne
   2. Rosacea
   3. Rash
   4. Tinea
2. excess growth hormone (prior epiphyseal plate closure); abnormal bone length
   1. Strain
   2. Rickets
   3. Rheumatism
   4. Gigantism
3. chronic metabolic disease characterized by an elevated body load of uric acid
   1. Rash
   2. Acne
   3. BMPs
   4. Gout
4. decreased bone mass; spicules thinner than normal bone
   1. Osteoporosis
   2. Osteoarthritis
   3. Osteomalacia
   4. Osteocalcin
5. recurring patches of scaly white or yellowish inflammation (head, face, chest, & back)
   1. Synovitis
   2. Psoriasis
   3. Seborrheic
   4. Bursitis

5 True/False Questions

1. Basal Cell Carcinoma → bone specific vit K-dependent calcium binding protein

   True        False

2. Rotator Cuff Tears → tears of 1 or more of the 4 tendons of the rotator cuff muscles (most typically involves the supraspinatus muscle)

   True        False

3. Addison disease → lysosomal storage disease; glycolipids are endocytosed & accumulate in neurons of brain

   True        False

4. Rheumatism → broad term for any pain in the supportive & locomotory organs of the body

   True        False

5. Osteomalacia → mineralization of bone matrix is impaired (soft bones); Vit D deficiency

   True        False