made up of mm fibers
made up of myofibrils
prot in Z line, connects Actin to Z line
connects Z line to M line
2 globular actin chains wound in to a double helix
sits betw 2 chains actin chains, length of 7 ctins
bins to actIn, holds it in place
binds to Tropomyosin
the act of moving myosin and actin toward the M line to shorten the sarcomere
Ryanodine SR Ca2+ channels
open in response to volt-dep Ca2+ channels to further inc intracellular Ca2+
single stimulus of mm
Max F gen by isometric twitch
amt of F in mm before contraction
initial F developed by mm before shortening (F gen to lift load)
measure of myosin ATPase activity (crossbridge rate)
spatial summation, increases proportion of mm fibers stimulated
max freq to get sustained contraction
tetanus with slight flux in F betw stimuli
tetanus with no flux in F betw stimuli
all the mm fibers innervated by the bundles of 1 motor neuron + the motorneuron itself
type of motor units that are recruited first
increased frequency of stimuli
increased recruitment of motor units
connect myofibrils to cells in smooth mm
unitary smooth mm
smooth mm that has gap junctions, found in GI, uterus, bladder
multiunit smooth mm
under neural control => fine control, found in iris, bl vessels
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