cartilage

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Created by:

feiyingluu  on October 5, 2010

Subjects:

histology

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cartilage

hyaline cartilage
composed of amorphous ground substances and Type II collagen fibrils, surrounded by perichondrium except in articular cartilage
most common cartilage in the body, found at the articular ends of long bones, nose, larynx, trachea, bronchi, serves as the skeleton of the fetus
regenerates poorly, often perichondrium forms scar tissue

collagen∼40% of total matrix, not discernible in histologic sections because fibrils very fine and have same refractive index as matrix
capsular matrix (matrix adjacent to the chondrocyte) poor in collagen but rich in glycosaminoglycans
stains deeply basophilic, also metachromatic and stains more intensely with periodic acid Shiff reaction (PAS) than other arears of matrix
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Terms

Definitions

hyaline cartilagecomposed of amorphous ground substances and Type II collagen fibrils, surrounded by perichondrium except in articular cartilage
most common cartilage in the body, found at the articular ends of long bones, nose, larynx, trachea, bronchi, serves as the skeleton of the fetus
regenerates poorly, often perichondrium forms scar tissue

collagen∼40% of total matrix, not discernible in histologic sections because fibrils very fine and have same refractive index as matrix
capsular matrix (matrix adjacent to the chondrocyte) poor in collagen but rich in glycosaminoglycans
stains deeply basophilic, also metachromatic and stains more intensely with periodic acid Shiff reaction (PAS) than other arears of matrix
perichondrium dense connective tissue region surrounding cartilage, except at articular surfaces
composed of an outer fibrous layer containing Type I collagen, fibroblasts and chondrongenic cells, contains blood vessels which supply nourishment for the avascular cartilage tissue
chondrogenic cells cells in the inner layer of the perichondrium, differentitate into chondroblasts
chondrocytesmatured chondroblasts located in lacunae of cartilage and are surrounded by matri,
located superficially, ovoid in shape and positioned so their longitudinal axes lie parallel to the cartilage surface
located deeper, more spherical in shape

osteogenous groups (groups of four to eight cells) found in young cartilage, suggestive of internal growth, also display an extensive Golgi apparatus, have an abundant rough endoplasmic reticulum and contain lipid droplets and glycogen deposits
cartilage growth hormones thyroxine, testosterone and growth hormone
cartilage growth inhibitor hormones hydrocortisone and estradiol
elastic cartilageoften found with hyaline cartilage, possess a perichondrium, grows by apposition, does not degenerate as readily as hyaline cartilage

located where support with flexibility is required, ear, auditory tube, epiglottis, matrix identical to hyaline cartilage, except also contains a network of elastic fibers-->yellowish color
fibrocartilageassociated with capsules and ligaments of joints, serves as transition between connective tissue and cartilage, lacks pericondrium, no appositional growth

found in conjunction with hyaline cartilage and other fibrosus tissues, located where support and tensile strength is of utmost importance, annulus fibrosus of the intervertebral discs, articular discs, pubic symphysis and at the intersections of some tendons and ligaments

composed of Type I collagen, chondroitin sulfate and dermatan sulfate, collagen fiber bundles arranged parallel to stress placed on the cartilage, chondrocytes lie in longitudinal columns between them

has characteristics which are intermediate between those of hyaline cartilage and dense connective tissue

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