Substances that have a hydrophilic and a hydrophobic parts.
Lipid molecules spontaniously assemble into bilayers. Easily seen by electron microscopy. (5nm)
Lipid bilayer that is held together by noncovalent interactions.
gasses can easily diffuse. small polar molecules cross with a little difficulty.
Main phospholipids found in animal cells. Contain a glycerol backbone bound to 2 fatty acids and a phosphate group.
(glycerol + 2 FAs + P04)
Phosphoglceride with (OCH2CH2NH3+) group attached to the phosphate.
Phosphoglyceride with a Serine AA attached to the phosphate. Has overall negative charge. When on extracellular lipid monolayer - marks cell as dead.
Phosphoglceride with (0CH2CH2N(CH3)3+) group attached to the phosphate.
Sphingomyelin and Sphingosine
Phospholipids without a glycerol backbone
"Water fearing". ex. 2-methyl propane
"Water loving". Forms H-bonds in water. ex. acetone, water
Amphipathic sterol containing 4 fused rings and an alcohol group. Stiffens regions of the plasma membrane.
Bilayers made in the form of spherical vesicles.
specialized domains of plasma membranes that can be analyzed by atomic force microscopy
amphiphilic protein, hydrophobic region pass through the membrane and interact with the hydrophobic tails.
Lipid linkage by which some membrane proteins are bound to the membrane. The protein is joined with a phsphatidylinositol anchor in the ER.
Peripheral membrane proteins
Protein that is attached to one face of a membrane only by noncovalent interactions with other membrane proteins. They can be removed by treatment with extreme pH or solutons of high or low ionic strength.
Integral Membrane Protein
Protein that is retained in a membrane by virtue of one or more domains that span or are embeded in the lipid bilayer.
Single-pass transmembrane proteins
Membrane protein in which the polypeptide chain crosses the lipid bilayer only once as an alpha helix.
Proteins respnsible for the transmembrane transport of ions and other small water-soluble molecules. Contain either a beta barrel or multiple alpha helicies.
Abundant protein associated with the cytosolic side of the plasma membrane in red blood cells, forming a network that supports the membrane.
Channel-forming proteins of outer memranes of bacteria, mitchondria, and chloroplasts.