DNA 3. Replication
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Created by:
-sophie on October 9, 2010
Subjects:
cellular and molecular biology
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20 terms
Terms | Definitions |
|---|---|
 What is the "start signal" for DNA replication? | Ori |
| DNA synthesis begins on one side of the ori and proceeds normally, what strand is this? | Leading strand |
| Synthesis of DNA strands in replication occurs in what direction? | 5'->3" |
| DNA synthesis on the other side of the ori, starts a short distance away from the ori and then works its way back to the ori; what strand is this? | Laggin strand |
| Small fragments of synthesized DNA on the lagging strand are called: | Okazaki fragments |
| The lagging strand is synthesized in continuous or disconrinuous DNA synthesis? | Discontinuous |
| What do DNA polymerases need to be able to add incoming dNTPs? | Primers |
| What do primers provide for DNA polymerases? | A free 3'-OH |
| Primase is a X-dependent, Y-synthesizing molecule; what is X and Y? | DNA, RNA |
| DNA polymerase III is a X-dependent, Y-synthesizing enzyme; what is X and Y? | DNA, DNA |
| What is a gap? | a missing base |
| What is a nick? | a cut (breakage in phosphodiester bonds) |
| Phosphodiester bond are what kind of bonds? | Covalent |
| Removing RNA bases and adding DNA is done by which polymerase? | DNA Polymerase I |
| DNA polymerase I has what kind of activity? | Exonuclease |
| To hydrolize phosphodiester linkages is to break/create the bond? | Break |
| Nicks are sealed in DNA replication by...? | DNA ligase |
| Which enzyme unwinds the DNA? | Helicase |
| Torque, created by helicase, is relieved by what? | Topoisomerases |
| What is another way of saying replication? | Amplification |
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