What are two ways that antimicrobial agents affect microorganisms?
1) disruption of the integrity of cells by altering cell walls and/or membranes
2) disruption of cellular metabolism and reproduction by interfering with structures of proteins and nucleic acids
What are the three main considerations in selecting a method of antimicrobial control?
1) the site to be treated
2) the relative susceptibility of the microorganism
3) environmental conditions (temperature, pH)