drugs that kill or inhibit the growth and replication of microorganisms in living tissue
drugs that are naturally occurring substances that are secreted by living organisms (bacteria, fungi) to inhibit other species
nonselective, toxic chemicals which are safe to be applied to the skin to kill microorganisms, but not safe to be given orally or parenterally
what is the number one requirement of bacteria in order for antibiotics that inhibit cell wall synthesis to work?
protein synthesis inhibiting drugs
antibiotics that inhibit cell wall synthesis are antagonized by what type of drugs?
no cell wall
what characteristic of mammalian cells make it so that they aren't damaged by cell wall synthesis inhibitors?
mammalian cell membrane is similar
what makes the use of antibiotics that disrupt bacterial cell membranes toxic?
what is the only route of administration for antibiotics that work to disrupt cell membranes?
are antibiotics that inhibit protein synthesis more bacteriostatic or bactericidal?
what is the major issue with antibiotics that inhibit DNA synthesis when they affect mammalian cell DNA
penicillins, cephalosporins, carbapenems/monobactams, glycopeptides, bacitracin
what are the 5 classes of cell wall inhibitors
route of admin for sodium and potassium salts
2 routes of admin for procaine salts
IM, IV, SQ
3 routes of admin for sodium salts
2 routes of admin for trihydrate salts