Physio Exam 3- DIGESTIVE

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The 3 agonists of the parietal cell?

Acetylcholine, gastrin, and histamine

Secretin stimulates the secretion of?

pancreatic juice and bile

Secretin inhibits what?

the action of gastrin on parietal cells

What action does CCK have on the pancreas?

secretion of enzymes

What action does CCK have on the gall bladder?

release of bile

What action does CCK have on the stomach?

gastric emptying

Which of the hormones of the GI tract stimulate the secretion of insulin?

GIP

Which paracrine agent has an inhibitory effect throughout the GI tract?

Somatostatin

Pacemaker cells for GI smooth muscle are called?

cells of Cajal

3 ways to trigger secretion of gastrin?

food in the stomach, peptides, and vagal stimulation

When present, gastrin causes the release of what?

HCl

The contraction during peristalsis is caused by the activation of neurons by the local plexus that release what?

Substance P and ACh

The relaxation during peristalsis is caused by the activation of neurons that release what?

NO, VIP, and ATP

Bile contains what?

bile salts, bile pigments, and bile acids

Starch digestion begins in the mouth when the salivary glands release what?

salivary amylase

Protein foods are largely acted on in the stomach by what?

pepsin

For the stomach protein-digesting enzyme to become active, what is needed?

HCl

The small intestine is protected by the action of hydrochloric acid in chyme by ______ which is ducted in by the pancreas.

bicarbonate rich fluid

This hormone stimulates the pancreas to release bicarbonate-rich juice.

Secretin

This hormone stimulates the pancreas to release enzyme-rich juice.

CCK

This hormone stimulates increased production of gastric juice.

Gastrin

This hormone causes the gallbladder to release stored bile.

CCK

This hormone causes the liver to increase its output of bile.

CCK and Secretin

Which type of cells secrete histamine?

ECL cells

Which type of cells secrete pepsinogen?

Chief cells

Which type of cells secrete mucous?

Goblet cells

Which type of cells secrete intrinsic factor for vitamin B12 absorption?

Parietal cells

Which type of cells secrete HCl?

Parietal cells

Which type of cells secrete the hormone gastrin?

G cells

It is stimulated by the presence of acid in the small intestine and stimulates bicarbonate release from the pancreas and bile ducts.

Secretin

It is stimulated by glucose and fat in the small intestine and increases insulin and amplifies the insulin responses to glucose.

GIP

It is inhibited by acid in the stomach and stimulates acid secretion from the stomach.

Gastrin

It is stimulated by amino acids and fatty acids in the small intestine and stimulates pancreatic enzyme secretion.

CCK

What does omeprazole do?

inhibits H+ K+ ATPase

Secretory fluxes of fluid are largely driven by the active transport of _______ ions into the lumen.

Chloride

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