Digestion and Absorption

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tlauria  on October 26, 2010

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vet 116 exam 3

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Digestion and Absorption

Digestion
the breakdown and absorption of food
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Digestion the breakdown and absorption of food
Herbivors eath plant matter, some are monogastric and some are ruminants
Carnivores eat flesh, all are monogastric
Omnivores eat it all, all are monogastric
Monogastric single chambered stomach
Ruminants multichambered, usually 4 chambers, mixing and fermentation
Prehension grasping of food with lips or teeth
Mastication mechanical breakdown of food, mostly chewing
Oral Cavity or Buccal Cavity where digestion begins
Salivary Glands has digestive and lubrication fuction, most domestic animals have three matching pairs
Perotid salivary glands below the ear canal, caudal to the mandible
Mandibular salivary glands ventral to parotid glands at caudal angle of the madible
Lingual Salivary glands sublingual salivary glands, medial to shafts of madible just under the base of the tounge
Sypathetic nervous system causes decreased salivation
Parasypathetic nervous system increases saliva output
Oropharynx the opening at the back of the throat through which food and air pass
Upper Arcade upper teeth, in maxilla and incisive bones
Lower Arcade lower teeth, in the madible
Incisors most rostral, front teeth, in incisive bone used for grasping
Canines typically longer than other teeth with pointed tips, tearing
Premolars rostral to molars, large occlusal surfaces, used for grinding and cutting
Molars the most caudal, used for grinding
Lingual surface inner surface of the lower arcade, faces the tongue (lingual refers to tongue)
Palatal Surface innter surface of the upper arcade, faces the hard palate
Labial Surface outer surface of the rostral teeth , faces the lips
Buccal Surface outer surface of caudal teeth, faces the cheeks
Occlusal Surface the surface used for chewing
Lower Case, Decidous teeth baby teeth
Upper Case permanent teeth
Carnassial teeth the upper 4th premoler and the lower 1st molar (site of deep infection for dogs and are difficult to extract
Esophagous a hollow tube that moves food towards the stomach
Lumen the open space where food travels
Mucosa the layer nearst the lumen, epithelial tissue and loose connective tissue
Submucosa a thicker layer beneath the mucosa, gland and denser connective tissue
Muscle Layer thick, has longitudinal and circular smooth muscle layers serves to propel material through the tract
Serosa the outermost layer of the GI tract, thin tough connective tissue
Cardia surrounding the opening of the esophagus, cirucular muscle maintains tone to reduce reflux of stomach material back into the esophagous
Fundus blind pouch that expands as more food is swallowed
Body middle of the stomach, also distensible
Cheif cells produce pepsinogen, enzyme precursor for pepsin
Mucus Cells produce protective mucus
I 3/3 C 1/1 P 4/4 M 2/3 canine adult dental formula
I 3/3 C 1/1 P 3/2 M 1/1 feline adult dental formula
Parietal or Oxyntic cels produce HCI
Antrum distal part that grinds up food and regulates hydrochloric acid
Pylorus muscular sphincter that regulates the movement of ingesta from the antrum protion of the stomach to the duodenum (small intestines) , also helps to prevent backflow from duodenum back into the stomach
Lesser curvature of the stomach the inside curvature
Greater curvature of the stomach the outside curvature
Rugae long muscular folds in the stomch lining which stretch , allow stomach to expand
Erosions breaks in the stomch mucosa
Gastric Ulcers deep erosions in the stomch mucosa
Gastritis inflammation of the stomach
Chyme semifluid partially digested food
Gastric Atony inhibition of stomch movement from sypathetic nervous input, ie from illness or surgery
Enterogastric reflex feedback loop from intestines
Gastrocolic reflex filling of stomach triggers signal for colon to empty, great for housetraining
Secretin released from the duodenum in response to excess stomach acid entering the small intestines
Cholecystokinin released in response to excess fats or proteins present in the duodenum
Gastrin causes increased HCL production & inhibits muscle activity of the fundus, greater relaxation and filling of the stomach
Pepsiongen/Pepsin from chief cells, is the precurser for the proteolytic enzyme
Mucins produced by goblet cells, main constituents of mucus coating which helps protect stomach lining
Bicarbonate Ion secreted onto the surface of the stomach to make the mucus coat more alkaline and thereby protect stomach lining from the HCL
Hydrochloric Acid produced by the parietal cells, starts breaking down food and converts pepsinogen to pepsin
Gastrin stretching of the body or antrum by food stimulates release
Acetylcholine from the parasympathetic nervous system , binds to recpetor on the parietal cell producing more HCL also causes more gastrin release
Duodenum small intestine attached to the stomach
Jejunum the longest portion of the smalls intestine
Ileum connects to the large intestine at the ileocecal sphincter(junction of ileum and colan)
Cecum blind pouch the sphincter regulates movement of material from teh small intestine to the colon
Mucosal layer built for absorption, large surface area augmented by villi and microvilli
Villi project off of the wall of the small intestine, finger like projections of the mucosa, each villus has thousands of microvilli
Microvillia (brush boarder) cells in this have many digestive enzymes and carrier molecules embedded in their cell membranes for the digestion and absorption or nutrients, vitimins and minerals
Crypt invagination around each villus, old cells are shed at the tip of the villus. The cells in this produce new cells to constantly replace old cells that are shed
Peristalsis coordinated contractions of longitudinal and circular muscle which move ingests or chyme through the intestine
Segmental Contractions Adequately mix chyme and expose fully to intestinal lining, slow movement, allow for water absorption. A lack of this movement causes diarrhea
Ileusa a lack of peristalsis resulting in decreasesd movment of ingesta through the intestine, can be caused by disease and stress
Polysaccharides starch, glycogen, sugars are complex carbohydrates
Amylase and enzyme released by the pancreas, breaks down carbohydrates
Proteases breaks down proteins into amino acids or dipeptides before they can be absorbed
5 basic proteases Etypsin, chymotrypsin, elastase, aminopeptidase, carboxypeptidase
Emulsification or Micelle Formation fats broken into smaller pieces, contractions of the stomach start the process
Triglycerides (fats) need lipase for pancreas, fat digesting enzymes that penetrate the bile acid coating and break triglycerides down into glycerol, fatty acids, and monoglycerides
Liver makes bile
Gall Bladder stores bile
Bile Duct carries bile from the gall bladder to the duodenum
Bile Acids prevent fat from re-clumping, are secreated into the duodenum from the liver, these help to prevent the fat droplets from recombining into larger globules again. These have a hydrophobic end to hold onto fats, and a hydrophilic end to hold onto water, making fats more soluble
Lipases fat digesting enzymes that penetrate the bile acid coating and break triglycerides down into glycerol, fatty acids, and monoglycerides
Fatty acids, Glycerol, and Monoclycerides micelles which can be absorbed through the brush border
Large Intestine water nad some electrolyte absorption, stores feces
Colon 3 portions which then connects to the rectum
Rectum terminal colon, stretching of the rectum stimulates defecation
Internal Sphincter smooth muscle and under autonomic control
External Sphincter skeletal muscle and under voluntary control
Liver largest organ inside the body, considered an accessory organ to digestion, filtration and detoxification
Glycogenesis the formation of glycogen from glucose
Glycogenolysis the breakdown of glycogen back into glucose
Gluconeogenesis the formation of glucose from amino acids
Pacreas located in the curve of the duodenum
Exocrine Function enzymes through ducts, fuction involves amylase, lipase, and proteases, also release bicarbonate into the duodenum to help maintain pH
Endocrine Function hormoses, ductless, involves maintence of blood glucose levels through the use of insulin and glucagon
Insulin secreted by beta cells in the islets of langerhans in the pancreas. Acts to move glucose from the blood into the cells.
Glucagon pancreatic hormone produced in the alpha cells has the opposite effect, mobilzes glucose from the liver to preven hypoglycemia

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